ID A0A1U7RDH2_ALLSI Unreviewed; 533 AA.
AC A0A1U7RDH2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 28-JAN-2026, entry version 32.
DE SubName: Full=Glucocorticoid modulatory element-binding protein 2 isoform X2 {ECO:0000313|RefSeq:XP_006021736.1};
GN Name=GMEB2 {ECO:0000313|RefSeq:XP_006021736.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006021736.1};
RN [1] {ECO:0000313|RefSeq:XP_006021736.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_006021736.1; XM_006021674.1.
DR AlphaFoldDB; A0A1U7RDH2; -.
DR GeneID; 102381717; -.
DR CTD; 26205; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:TreeGrafter.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:TreeGrafter.
DR FunFam; 3.10.390.10:FF:000003; glucocorticoid modulatory element-binding protein 1 isoform X2; 1.
DR Gene3D; 3.10.390.10; SAND domain-like; 1.
DR InterPro; IPR059099; GMEB1/2/Spe-44_dom.
DR InterPro; IPR010919; SAND-like_dom_sf.
DR InterPro; IPR000770; SAND_dom.
DR PANTHER; PTHR10417; GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN; 1.
DR PANTHER; PTHR10417:SF2; GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 2; 1.
DR Pfam; PF01342; SAND; 1.
DR Pfam; PF25892; Spe-44; 1.
DR SMART; SM00258; SAND; 1.
DR SUPFAM; SSF63763; SAND domain-like; 1.
DR PROSITE; PS50864; SAND; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 81..163
FT /note="SAND"
FT /evidence="ECO:0000259|PROSITE:PS50864"
FT COILED 309..343
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 533 AA; 57090 MW; 75B0C9415F8B28B0 CRC64;
MATPDVSVHM EEVVVVTTPD NMVDGTGVEE VKTVLVTTNL SQHGGDLNED TLESENAAAA
AAAAFTASAH LKEAVLVKMA EEEDSLEAEI VYPITCGDSK ANLIWRKFVC PGINVKCVQY
DDHLISPKEF VHLAGKSTLK DWKRAIRMNG IMLRRIMDSG ELDFYQHTKV CSNTCRSTKI
DLTGARVSLT SQTSTEYFPL TPASADVNGS PATITIETCE EATDWTTTIG DDTFAFWRGL
KDAGLLEEVI QEFHQELVEN MKGLQQRVQD PPLQLSDAVL LNNIVQNFGM LDLVKKVLAS
HKCQMDRSRE QYTRDLAALE QQCDEHRKRA KELKHKSQHL NNVLMTLTPV SVPAPLKRPR
LTRATSGPAA ITSHVLSQSA QIAVAPGVPI SQLASLPLGK VVSALPTSVL GKSTSQTSAV
SSPASPLLGG YTVLASAGSS FPNAVEIHPD ASNLTVLSTA AIQDGSTVVK VVSPFQLLTL
PGLGTAIQNV TQMAPGGSTI VTVPSSAVEG ATASDEHTTT IEVTTVAEES EQK
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