ID A0A1U7S448_ALLSI Unreviewed; 847 AA.
AC A0A1U7S448;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 28-JAN-2026, entry version 38.
DE SubName: Full=E3 ubiquitin-protein ligase ZNF598 {ECO:0000313|RefSeq:XP_006024063.1};
GN Name=ZNF598 {ECO:0000313|RefSeq:XP_006024063.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_006024063.1};
RN [1] {ECO:0000313|RefSeq:XP_006024063.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
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DR RefSeq; XP_006024063.1; XM_006024001.3.
DR AlphaFoldDB; A0A1U7S448; -.
DR STRING; 38654.A0A1U7S448; -.
DR GeneID; 102379197; -.
DR KEGG; asn:102379197; -.
DR CTD; 90850; -.
DR eggNOG; KOG2231; Eukaryota.
DR InParanoid; A0A1U7S448; -.
DR OrthoDB; 3838338at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0043022; F:ribosome binding; IEA:TreeGrafter.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:TreeGrafter.
DR GO; GO:0072344; P:rescue of stalled ribosome; IEA:InterPro.
DR InterPro; IPR057634; PAH_ZNF598/HEL2.
DR InterPro; IPR044288; ZNF598/HEL2.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR059042; Znf_C2H2_ZNF598.
DR PANTHER; PTHR22938:SF0; E3 UBIQUITIN-PROTEIN LIGASE ZNF598; 1.
DR PANTHER; PTHR22938; ZINC FINGER PROTEIN 598; 1.
DR Pfam; PF23202; PAH_ZNF598; 1.
DR Pfam; PF25447; RING_ZNF598; 1.
DR Pfam; PF23208; zf_C2H2_ZNF598; 1.
DR SMART; SM00355; ZnF_C2H2; 5.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 134..155
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT REGION 239..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 314..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..341
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..563
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 847 AA; 94674 MW; 2CC7A092C2453C43 CRC64;
MRALCGVRYC AVCRDELAQV VFGKKLSSFS TIVLNQLQHE KKYDIYFADG KVYALYRKLL
QHECPLCPHV QPFNTIVELE QHMRKQHELF CCKLCVKHLK IFTYERKWYS RKDLARHRIH
GDPDDTSHRG HPLCKFCDER YLDNDELLKH LRRDHYFCHF CDSDGAQEYY SDYEYLREHF
REKHFLCEEG RCSTEQFTHA FRTEIDYKAH KTACHSKNRA EARQNRQIDL QFNYAPRHQR
RNESVVTGED YEGVERYNRQ GRPVRTSVRG GQQNRRGSWR YKRSLGGQTE CFGKRRGEEE
DRDIAAAVRA SIAAKRQEEK KRVEEKEDSS RGKKEELRDA ETSNAKRVPK PSSEATVPKE
AAANGPLSQD NFPAIGSAVG SLQGCSAAQP VSVKLKEEDF PSLSSSAAPT VSTGLSLTYT
VTAKKTAFQE EDFPALVSKV KPTNKTVSNI TSAWNNGSNK NVVKAIGSSS SSSNQLAKKA
APPNSSKGGK KSNKSPQSDD EDAGNGLTTQ KIRNAPTMVD VSSLLAASTS QTFTKVGKKK
KVGVEKQRPP SPPASEENSP PGSLEKVVEA KQMPNALANV QAPDRSAAVM NGHSEKSVAV
CNTPKEPPGL KKPAATNQCP LPQEDFPALG SSGPARMPPP GFNSVVLLKS PPPGLSVSVS
KPPPGFPVIP STNVSEPVTT SLKEPTPSQG TYLIPEHFQQ RNIQLIQSIK EFLQSDESRF
NKFKTHSGQF RQGLMSAAQY YKSCRDLLGD NFRRIFNELL VLLPDTAKQQ ELLSAHNDFK
VQEKQGSNKP RKNKKNAWET DPGADLDCCI CPTCKQVLTH QDLATHKALH LEDEEFPSLQ
AISRIIS
//
