ID A0A1U7X978_NICSY Unreviewed; 874 AA.
AC A0A1U7X978;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 28-JAN-2026, entry version 35.
DE SubName: Full=NF-X1-type zinc finger protein NFXL2 {ECO:0000313|RefSeq:XP_009783479.1};
GN Name=LOC104232079 {ECO:0000313|RefSeq:XP_009783479.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009783479.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009783479.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009783479.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NFX1 family.
CC {ECO:0000256|ARBA:ARBA00007269}.
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DR RefSeq; XP_009783479.1; XM_009785177.1.
DR AlphaFoldDB; A0A1U7X978; -.
DR STRING; 4096.A0A1U7X978; -.
DR GeneID; 104232079; -.
DR KEGG; nsy:104232079; -.
DR eggNOG; KOG1952; Eukaryota.
DR OrthoDB; 536399at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR CDD; cd06008; NF-X1-zinc-finger; 6.
DR InterPro; IPR034078; NFX1_fam.
DR InterPro; IPR000967; Znf_NFX1.
DR PANTHER; PTHR12360:SF1; NF-X1-TYPE ZINC FINGER PROTEIN NFXL1; 1.
DR PANTHER; PTHR12360; NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1; 1.
DR Pfam; PF01422; zf-NF-X1; 11.
DR SMART; SM00438; ZnF_NFX; 11.
DR SUPFAM; SSF57850; RING/U-box; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT TRANSMEM 832..850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 189..207
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 241..260
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 294..313
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 348..368
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 401..420
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 428..447
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 485..506
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 514..559
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 596..629
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 639..657
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 702..723
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 782..810
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..27
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 782..804
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 874 AA; 97746 MW; F905C417939E3786 CRC64;
MTSWSATVAP PLSPPSSDSD SDSATISDSH HHRHSDLSST IFKSYLEHSS GDHNNQQQQQ
HDLIKIQSFL TSSRSGALSC LICLERIRPS DPTWSCSSGC FAVFHLHCIQ SWAVQCSNLA
AARAVTRAAT PNDSSLLWHC PKCRVEYSKS QIPKNYYCFC GKLPDPPHDP WVLPHSCNEI
CGRPLKYNCG HHCLLLCHPG PCPACPKLVK SNCFCGAVED VKRCGFKNFS CNGVCKKLLD
CKTHRCSETC HEGNCPPCKA KGIYKCQCGK LEMKRECFDR FFRCENPCVK LLGCGRHKCE
RGCHEGDCGD CPLQGKRTCP CGKRFYEGIA CDAPVSVCGA TCGKMLSCGF HRCPERCHRG
PCIETCRVVV TKSCRCGSYR KQVPCYQDMT CERKCQKMRD CGRHACKRKC CDGDCPPCSE
MCDRKLRCRN HKCPAPCHRG ACAPCPVMVT ISCLCGVTHF EVPCGAEAEQ TPPKCRKPCR
VDRLCRHASN CKPHRCHYGA CPPCRLLCDE EYPCGHKCEL RCHGPTQPPL PEFTLKPKKR
RPNNQTEPTP GSSCPPCPQL VWRSCWGNHV GAERMMVCSD RTVFSCDNLC GNPLPCGNHY
CTKVCHALVS SASKLYGSRR PESCEECTLP CQQERKPTCR HPCPLRCHPG ECPPCKALIK
RSCHCGSMVH VFECIYYNSL SAKEQLTVRS CGGPCHRKLP NCTHLCPEIC HPGECSSPDQ
CSKKVTARCG CQNLKKELVC KDVQAAYRSN GTDPKDVSRN QYGLGILPCN SDCRSKVKAA
EGELQHRKSK APEEKEPETK DNVMKRRRRK GRVLEDKKTS ILQRIFAGIK KFLLFVIIII
ALIASVYLGY KGLLWLSDWM NEAEIQRQRR YSRT
//
