ID A0A1U8JVN2_GOSHI Unreviewed; 676 AA.
AC A0A1U8JVN2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 28-JAN-2026, entry version 35.
DE SubName: Full=BTB/POZ domain-containing protein At5g66560 {ECO:0000313|RefSeq:XP_016692324.1};
GN Name=LOC107909351 {ECO:0000313|RefSeq:XP_016692324.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000818029, ECO:0000313|RefSeq:XP_016692324.1};
RN [1] {ECO:0000313|Proteomes:UP000818029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000818029};
RX PubMed=32313247; DOI=10.1038/s41588-020-0614-5;
RA Chen Z.J., Sreedasyam A., Ando A., Song Q., De Santiago L.M.,
RA Hulse-Kemp A.M., Ding M., Ye W., Kirkbride R.C., Jenkins J., Plott C.,
RA Lovell J., Lin Y.M., Vaughn R., Liu B., Simpson S., Scheffler B.E., Wen L.,
RA Saski C.A., Grover C.E., Hu G., Conover J.L., Carlson J.W., Shu S.,
RA Boston L.B., Williams M., Peterson D.G., McGee K., Jones D.C., Wendel J.F.,
RA Stelly D.M., Grimwood J., Schmutz J.;
RT "Genomic diversifications of five Gossypium allopolyploid species and their
RT impact on cotton improvement.";
RL Nat. Genet. 52:525-533(2020).
RN [2] {ECO:0000313|RefSeq:XP_016692324.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the NPH3 family. {ECO:0000256|PROSITE-
CC ProRule:PRU00982}.
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DR RefSeq; XP_016692324.1; XM_016836835.2.
DR AlphaFoldDB; A0A1U8JVN2; -.
DR STRING; 3635.A0A1U8JVN2; -.
DR PaxDb; 3635-A0A1U8JVN2; -.
DR GeneID; 107909351; -.
DR KEGG; ghi:107909351; -.
DR OMA; PAMEGRW; -.
DR OrthoDB; 624345at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000818029; Chromosome D03.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.710.10; Potassium Channel Kv1.1, Chain A; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR043454; NPH3/RPT2-like.
DR InterPro; IPR027356; NPH3_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR32370; OS12G0117600 PROTEIN; 1.
DR Pfam; PF03000; NPH3; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS51649; NPH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000818029};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 21..125
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 246..535
FT /note="NPH3"
FT /evidence="ECO:0000259|PROSITE:PS51649"
FT REGION 61..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..676
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 598..625
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 61..70
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..93
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 564..577
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..666
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..676
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 676 AA; 75951 MW; 4BB8D69EE8C74D02 CRC64;
MAADKPSSKG QAWFCATGLP SDIIIEVDDM TFHLHKFPLI SKSRKIDRLI EEQGKKSSTV
TVTKQKQRVT GNEIEEEEET EEYQDQQDDE EEDRYQISLQ DFPGGSDAFE TAAKFCYGVK
IDLSSSTVVP LRCAAEFLEM TDEYSEDNLI SKTERFLSQS VFKSLKASIK ALKSCESVMT
LAESLGIVER LIDSIALRAS STDPTLFGWP VNDGIVEAKG ASAQALWNGI ETGLRRKALA
RTSNVESWFE DLALLSLPLF KRLISTLKRR DLSPEVIESC LMCYAKKYIP GTSRSNRKPS
SSLAAAISES EQRELLETII SNLPLEKTHS SSSTATRLLF GLLRTANILN ASESSKAALE
KKIGFQLEQA TLDDLLIPSY SYLNETLYDV DCIERILGYF LDGLEERNAA GIEAENEGNN
DNIINSSRLP ALMLVGKLID GYLSEIASDA NLKPEKFYNL AISLPDQARN FDDGLYRAVD
VYLKAHPWIP ESEREKICGV LDCQKLTLEA CTHAAQNERL PLRAVVQVLF FEQLQLRHAI
AGTLLAAETA PMNAGRLSGT RRDDDEEEEE QQDEEEERVA MSRGEQGSTT WRAAVRENQV
LRLDMDSMRT RVHQLERECS TMKKVIQKIE KGNPRGSGWR GSLNKRLGCK FKTQVCDSHE
STVTETRRRR HHHHQE
//
