ID A0A1U8MW27_GOSHI Unreviewed; 604 AA.
AC A0A1U8MW27;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 28-JAN-2026, entry version 31.
DE RecName: Full=Growth-regulating factor {ECO:0000256|RuleBase:RU367127};
GN Name=LOC107941922 {ECO:0000313|RefSeq:XP_016731037.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000818029, ECO:0000313|RefSeq:XP_016731037.1};
RN [1] {ECO:0000313|Proteomes:UP000818029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000818029};
RX PubMed=32313247; DOI=10.1038/s41588-020-0614-5;
RA Chen Z.J., Sreedasyam A., Ando A., Song Q., De Santiago L.M.,
RA Hulse-Kemp A.M., Ding M., Ye W., Kirkbride R.C., Jenkins J., Plott C.,
RA Lovell J., Lin Y.M., Vaughn R., Liu B., Simpson S., Scheffler B.E., Wen L.,
RA Saski C.A., Grover C.E., Hu G., Conover J.L., Carlson J.W., Shu S.,
RA Boston L.B., Williams M., Peterson D.G., McGee K., Jones D.C., Wendel J.F.,
RA Stelly D.M., Grimwood J., Schmutz J.;
RT "Genomic diversifications of five Gossypium allopolyploid species and their
RT impact on cotton improvement.";
RL Nat. Genet. 52:525-533(2020).
RN [2] {ECO:0000313|RefSeq:XP_016731037.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- FUNCTION: Transcription activator. {ECO:0000256|RuleBase:RU367127}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU01002, ECO:0000256|RuleBase:RU367127}.
CC -!- DOMAIN: The QLQ domain and WRC domain may be involved in protein-
CC protein interaction and DNA-binding, respectively.
CC {ECO:0000256|RuleBase:RU367127}.
CC -!- SIMILARITY: Belongs to the GRF family. {ECO:0000256|ARBA:ARBA00008122,
CC ECO:0000256|RuleBase:RU367127}.
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DR RefSeq; XP_016731037.1; XM_016875548.2.
DR AlphaFoldDB; A0A1U8MW27; -.
DR STRING; 3635.A0A1U8MW27; -.
DR PaxDb; 3635-A0A1U8MW27; -.
DR GeneID; 107941922; -.
DR KEGG; ghi:107941922; -.
DR OrthoDB; 1927209at2759; -.
DR Proteomes; UP000818029; Chromosome A05.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:UniProtKB-UniRule.
DR GO; GO:0099402; P:plant organ development; IEA:UniProtKB-ARBA.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR014978; Gln-Leu-Gln_QLQ.
DR InterPro; IPR031137; GRF.
DR InterPro; IPR014977; WRC_dom.
DR PANTHER; PTHR31602:SF51; GROWTH-REGULATING FACTOR; 1.
DR PANTHER; PTHR31602; GROWTH-REGULATING FACTOR 5; 1.
DR Pfam; PF08880; QLQ; 1.
DR Pfam; PF08879; WRC; 1.
DR SMART; SM00951; QLQ; 1.
DR PROSITE; PS51666; QLQ; 1.
DR PROSITE; PS51667; WRC; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|RuleBase:RU367127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU01002}; Reference proteome {ECO:0000313|Proteomes:UP000818029};
KW Transcription {ECO:0000256|RuleBase:RU367127};
KW Transcription regulation {ECO:0000256|RuleBase:RU367127}.
FT DOMAIN 144..179
FT /note="QLQ"
FT /evidence="ECO:0000259|PROSITE:PS51666"
FT DOMAIN 214..258
FT /note="WRC"
FT /evidence="ECO:0000259|PROSITE:PS51667"
FT REGION 278..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 219..229
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01002"
FT MOTIF 247..254
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01002"
FT COMPBIAS 278..287
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..574
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..604
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 604 AA; 65253 MW; 9C053340CF52035D CRC64;
MDFGVVGFEG FIGSETATGF SSLGSDHQET SQKWYGSGGL FKQERSCNNE DELRSSKLAK
IHDDFSGSSK PLMFHHRNTS LRSNASIFFD EQEEQQMLSF SAPKPDALSV DRSSKNVTFP
HIYLTGYNNG GFNGANMHGV CKGPFTPCQW MELEHQALIL KYILANVPVP SNLLLPIRKS
LDSTDFSSFS GGHFRSNTSM GWEAFQFGFS NNTDPEPGRC RRTDGKKWRC SRDAVAGQKY
CERHMNRGRH RSRKPVEGQP GHSVTATAAI TSKLMPNVSS SSASAVGPVG GSGEPNILTS
ARQKYENLQP GGTSNLSAAA SLNRSILNKD TVGEKMPYTA AGLSMISPNG DLKSKENPFL
IPKQPISYEE NLRNGFGVVS SGELNPSHKS SSMINSRNFG SSQDLTSQET DSQQSFRRFI
DDRPKSQSHC SAISWPELDV QSYRTQLSVS IPMAASDFTS TTSSPNNENL TSSPLRLSRE
FDPINIGLGV GNVVNESNQK QANWIPVSWG TSIGGPLGEA LHSNGNTMVD LKNSSLLNLM
TEGSENSPLV GSSPTGVLQK TTFASLSNSS AGSSPENNKT PEGVSHCNDL LGSNLVESSS
LPAT
//
