ID A0A1V2L1J1_CYBFA Unreviewed; 209 AA.
AC A0A1V2L1J1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 08-OCT-2025, entry version 30.
DE SubName: Full=Mitotic spindle checkpoint component mad2 {ECO:0000313|EMBL:ONH65640.1};
GN ORFNames=BON22_4492 {ECO:0000313|EMBL:ONH65640.1};
OS Cyberlindnera fabianii (Yeast) (Hansenula fabianii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Phaffomycetales; Phaffomycetaceae; Cyberlindnera.
OX NCBI_TaxID=36022 {ECO:0000313|EMBL:ONH65640.1, ECO:0000313|Proteomes:UP000189513};
RN [1] {ECO:0000313|Proteomes:UP000189513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=65 {ECO:0000313|Proteomes:UP000189513};
RX PubMed=28385833; DOI=10.1128/genomeA.00064-17;
RA van Rijswijck I.M.H., Derks M.F.L., Abee T., de Ridder D., Smid E.J.;
RT "Genome sequences of Cyberlindnera fabianii 65, Pichia kudriavzevii 129,
RT and Saccharomyces cerevisiae 131 isolated from fermented masau fruits in
RT Zimbabwe.";
RL Genome Announc. 5:E00064-E00064(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MAD2 family.
CC {ECO:0000256|ARBA:ARBA00010348}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONH65640.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MPUK01000010; ONH65640.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V2L1J1; -.
DR STRING; 36022.A0A1V2L1J1; -.
DR VEuPathDB; FungiDB:BON22_4492; -.
DR OMA; WQFDVEI; -.
DR Proteomes; UP000189513; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0000776; C:kinetochore; IEA:TreeGrafter.
DR GO; GO:0033597; C:mitotic checkpoint complex; IEA:UniProtKB-ARBA.
DR GO; GO:0005654; C:nucleoplasm; IEA:TreeGrafter.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:TreeGrafter.
DR FunFam; 3.30.900.10:FF:000002; Mitotic spindle assembly checkpoint protein MAD2A; 1.
DR Gene3D; 3.30.900.10; HORMA domain; 1.
DR InterPro; IPR003511; HORMA_dom.
DR InterPro; IPR036570; HORMA_dom_sf.
DR InterPro; IPR045091; Mad2-like.
DR PANTHER; PTHR11842; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2; 1.
DR PANTHER; PTHR11842:SF11; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A; 1.
DR Pfam; PF02301; HORMA; 1.
DR SUPFAM; SSF56019; The spindle assembly checkpoint protein mad2; 1.
DR PROSITE; PS50815; HORMA; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000189513}.
FT DOMAIN 13..203
FT /note="HORMA"
FT /evidence="ECO:0000259|PROSITE:PS50815"
SQ SEQUENCE 209 AA; 23783 MW; 7C41C1C9F46BDC1F CRC64;
MTDAPTRSNL ALRGSARTVA EYFEYAINSI LYQRGIYPAE DFHVVRKYGL SMLVTADEDV
KHYIRKIVTQ LHRWVVQDKV SRLVLAVVNK DDAVVVERWQ FDLQVFDETS THAAENIPID
AGDKTEEMMQ KEIQATIRQI TASVTFLPAL DSGDYTFNVL VYADANAKVP SEWIDSDTKD
IQNAEKVKFR SFSTNSHKVD TLVSYRLGN
//
