ID A0A1V4K575_PATFA Unreviewed; 466 AA.
AC A0A1V4K575;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 10-JUN-2026, entry version 18.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN ORFNames=AV530_014074 {ECO:0000313|EMBL:OPJ79612.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Columbimorphae; Columbiformes;
OC Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ79612.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ79612.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ79612.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ79612.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ79612.1}.
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DR EMBL; LSYS01004359; OPJ79612.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4K575; -.
DR OrthoDB; 27389at2759; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:TreeGrafter.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR047887; ARHGAP20_PH.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23179; T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED; 1.
DR PANTHER; PTHR23179:SF26; T-CELL ACTIVATION RHO GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF22286; RHG20_PH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|PROSITE-ProRule:PRU00172};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648}.
FT DOMAIN 135..342
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 352..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..403
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..455
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..466
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 466 AA; 51876 MW; 0DE75810F912C899 CRC64;
MGQANCCCGS RQALSDTKPV LSKDVWLTWG IKRSERCLLL PQEELLITEL QRGTNLRPEL
CLALGQLWML SGKEAVGKEE EKEEEKSGNE DRTCLIIIWP TGSRVAHFRR VVLPCAMARQ
ERAGRLRCSR ALFGRPLAAL CGEDITLPQP IQELLAVLQG EGPLIEGILH RAVSGTADQE
LHKALDCGLD FDLGSQPVDL LAVILKFLVI DLYKMWMSAM QKTSMEEKME EVKVVAKKLP
EANLLLLKKL LTPLQHIRRM SSNNLATCIG PNLLSPPKEE LLPLEAMLEV TQKARCLDQL
TAAFPAHQSL AARSSLDNFS PLEPTLVNML VEFMIENYGD IFQDEVAGLS CPSAKESSAP
MERSTDLHLE EKSGPAGRTD EDHEVKTFLD ARPSRLDNLK EAGGDTVVEG KMAESPRVLT
PITPKSAAES LQHLEQLRSL SDHRRFAGSP QDKEKRRNLK RKLAWE
//
