ID A0A1V6Y8D7_PENNA Unreviewed; 489 AA.
AC A0A1V6Y8D7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 28-JAN-2026, entry version 28.
DE RecName: Full=DAGKc domain-containing protein {ECO:0000259|PROSITE:PS50146};
GN ORFNames=PENNAL_c0031G04271 {ECO:0000313|EMBL:OQE83669.1},
GN PNAL_LOCUS7293 {ECO:0000313|EMBL:CAG8193974.1};
OS Penicillium nalgiovense.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=60175 {ECO:0000313|EMBL:OQE83669.1, ECO:0000313|Proteomes:UP000191691};
RN [1] {ECO:0000313|EMBL:OQE83669.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 13039 {ECO:0000313|EMBL:OQE83669.1};
RA Nielsen J.C., Nielsen J.;
RT "Uncovering the secondary metabolism of Penicillium species provides
RT insights into the evolution of 6-MSA pathways.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000191691}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 13039 {ECO:0000313|Proteomes:UP000191691};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
RN [3] {ECO:0000313|EMBL:CAG8193974.1}
RP NUCLEOTIDE SEQUENCE.
RA Branca A.L. A.;
RL Submitted (JUL-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQE83669.1}.
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DR EMBL; CAJVNV010000432; CAG8193974.1; -; Genomic_DNA.
DR EMBL; MOOB01000031; OQE83669.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6Y8D7; -.
DR STRING; 60175.A0A1V6Y8D7; -.
DR OMA; TMGNFYA; -.
DR OrthoDB; 3853857at2759; -.
DR Proteomes; UP000191691; Unassembled WGS sequence.
DR Proteomes; UP001153461; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0016020; C:membrane; IEA:TreeGrafter.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0001727; F:lipid kinase activity; IEA:TreeGrafter.
DR GO; GO:0046512; P:sphingosine biosynthetic process; IEA:TreeGrafter.
DR Gene3D; 2.60.200.40; -; 1.
DR Gene3D; 3.40.50.10330; Probable inorganic polyphosphate/atp-NAD kinase, domain 1; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR055916; DUF7493.
DR InterPro; IPR050187; Lipid_Phosphate_FormReg.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR045540; YegS/DAGK_C.
DR PANTHER; PTHR12358:SF31; ACYLGLYCEROL KINASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF24321; DUF7493; 1.
DR Pfam; PF19279; YegS_C; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000191691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 118..257
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 489 AA; 52895 MW; 02B2B5A9B591A7CE CRC64;
MSSQDDSSEP HDTTLIVESV SLTIGADSLL ILDDRPAKAD RSCCGLLQPK PETNHAISLY
NILGAEVTAS NLVIAYAQHS AKNDVSVTTV QYPISEKEKV AIERWAQQLL DAAYAKALRG
KRLKVLVNPF GGKGTAASLY QRYAAPVFAA AKCQLDVQNT EYRGHALEIA ENLDIDAYDA
VVCCSGDGLP YEVFNGLGKR PDARKALAQT AVALLPCGSG NGLTWNAFGT GSVSIAALAI
VKGLRTPLDL VSISQKDSRT LSFLSQSFGI VAECDLGTEN IRWMGAQRFT YGFLIRLMRQ
TIWPCDIAVK VEIGDKEAIK EHYAAWSTRP QDPDADSKRL GIAAESPGLP ELKYGTVTDE
LPQGWQVISG ETMGNFYAGN MAIMSKDTNM FPATLPDDGL MDVVTIDGTV SRATALTMMN
EIPSGRFFDM PDLNVRKASA FRLVPHQKEG YISIDGERVP FEAFQAEVHQ GLGTILTKSG
CIYEAAGPR
//
