ID A0A1V9A953_SACPI Unreviewed; 583 AA.
AC A0A1V9A953;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 28-JAN-2026, entry version 33.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=B1813_03685 {ECO:0000313|EMBL:OQO93655.1};
OS Saccharomonospora piscinae.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharomonospora.
OX NCBI_TaxID=687388 {ECO:0000313|EMBL:OQO93655.1, ECO:0000313|Proteomes:UP000192591};
RN [1] {ECO:0000313|EMBL:OQO93655.1, ECO:0000313|Proteomes:UP000192591}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LRS4.154 {ECO:0000313|EMBL:OQO93655.1,
RC ECO:0000313|Proteomes:UP000192591};
RA Alonso-Carmona G.S., De La Haba R., Vera-Gargallo B.,
RA Sandoval-Trujillo A.H., Ramirez-Duran N., Ventosa A.;
RT "Draft genome of Saccharomonospora sp. 154.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQO93655.1}.
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DR EMBL; MWIH01000003; OQO93655.1; -; Genomic_DNA.
DR RefSeq; WP_081190614.1; NZ_MWIH01000003.1.
DR AlphaFoldDB; A0A1V9A953; -.
DR STRING; 1962155.B1813_03685; -.
DR Proteomes; UP000192591; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:OQO93655.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000192591}.
FT DOMAIN 1..169
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 583 AA; 61695 MW; 090D90BD69A36812 CRC64;
MHVLATAGHV DHGKSTLVRA LTGMEPDRLA EERRRGLTVE LGFVWTQVRE RTFAFVDVPG
HRRFVPTMLA GTGPVAAVLF VVAADEGWQA QSTEHLAALD ALGVRHGLLV VTKADRADPG
PVLADAGERL ALTSLGRVSA VAVSVRSGRG LAALRAELAA LGDRLPVPDT GADVRLWIDR
AFSVRGAGTV VTGTLGAGTL RVGDELALGR SGRRCVVRGL ESLGRPSAAV AAVARVAVNL
RGLDRHDLSR GDTLLTPGRW RHIDELDVRL RGAKAGELHR ELVLHLGAAA VACRVRPLAT
DVVRLSLSRA LPVRAGDRGL VRDPGEHRVP AGVDVLDPSP PALRRRGAAR ARAVELAGDP
AAAFVRRHGA VALDELRALG WQSHASERVG RWAVADGLLD EAATRAREAV ARAHARDPLS
PGLALEELRR ELDLPGELVA VAVGRTDLVV GDGLVRPAGA APSLPAPVER AVREVERRLA
REPFAAPDAH DLAGLGLGPR QLAAAERAGR LLRLADGVVA RPDAVEAATA ILSRLPEPFT
VSEARRALGT TRRVAVPLLE LLDAQGHTRR DTDGRRTVRG AHT
//
