ID   A0A1W2TUQ0_ROSNE        Unreviewed;       225 AA.
AC   A0A1W2TUQ0;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   28-JAN-2026, entry version 28.
DE   RecName: Full=Iron-sulfur assembly protein 1 {ECO:0000256|ARBA:ARBA00071673};
GN   ORFNames=SAMD00023353_8000360 {ECO:0000313|EMBL:GAP92342.2};
OS   Rosellinia necatrix (White root-rot fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Xylariaceae; Rosellinia.
OX   NCBI_TaxID=77044 {ECO:0000313|EMBL:GAP92342.2};
RN   [1] {ECO:0000313|EMBL:GAP92342.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W97 {ECO:0000313|EMBL:GAP92342.2};
RA   Kanematsu S.;
RT   "Draft genome sequence of Rosellinia necatrix.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the assembly of mitochondrial and cytoplasmic
CC       iron-sulfur proteins. Probably involved in the binding of an
CC       intermediate of Fe/S cluster assembly. {ECO:0000256|ARBA:ARBA00054873}.
CC   -!- SIMILARITY: Belongs to the HesB/IscA family.
CC       {ECO:0000256|ARBA:ARBA00006718}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DF977525; GAP92342.2; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W2TUQ0; -.
DR   STRING; 77044.A0A1W2TUQ0; -.
DR   OMA; MPRVHET; -.
DR   OrthoDB; 333486at2759; -.
DR   Proteomes; UP000054516; Unassembled WGS sequence.
DR   GO; GO:0005759; C:mitochondrial matrix; IEA:EnsemblFungi.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:TreeGrafter.
DR   GO; GO:0005506; F:iron ion binding; IEA:EnsemblFungi.
DR   GO; GO:0044572; P:[4Fe-4S] cluster assembly; IEA:EnsemblFungi.
DR   GO; GO:0009102; P:biotin biosynthetic process; IEA:EnsemblFungi.
DR   GO; GO:0051604; P:protein maturation; IEA:EnsemblFungi.
DR   FunFam; 2.60.300.12:FF:000001; Iron-binding protein IscA; 1.
DR   Gene3D; 2.60.300.12; HesB-like domain; 1.
DR   InterPro; IPR016092; ATAP.
DR   InterPro; IPR000361; ATAP_core_dom.
DR   InterPro; IPR050322; Fe-S_cluster_asmbl/transfer.
DR   InterPro; IPR017870; FeS_cluster_insertion_CS.
DR   InterPro; IPR035903; HesB-like_dom_sf.
DR   NCBIfam; TIGR00049; iron-sulfur cluster assembly accessory protein; 1.
DR   PANTHER; PTHR10072:SF41; IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR10072; IRON-SULFUR CLUSTER ASSEMBLY PROTEIN; 1.
DR   Pfam; PF01521; Fe-S_biosyn; 1.
DR   SUPFAM; SSF89360; HesB-like domain; 1.
DR   PROSITE; PS01152; HESB; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054516}.
FT   DOMAIN          122..221
FT                   /note="Core"
FT                   /evidence="ECO:0000259|Pfam:PF01521"
FT   REGION          37..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..49
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..64
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   225 AA;  25232 MW;  52D46F70E2DAE1CE CRC64;
     MVLRRGPGLL LNCLNAVTIS SARPCLRVLR RFSQTQSWAA PENQQTPLPF QSYPLPSRLP
     SSPRNEPIPE TPIANPIPLV HETRAPSQPE TIAQPDKTLG QEAQKPKPIP LKRKLRPRKA
     ALKLTPTAVE QLRQLLDQPE PKLIKVGVRN RGCSGLAYHL EYVDKPAAFD EEVEQDGVKV
     VIDSKALFSI IGSEMDWVED KLNQRFIFRN PNIKEECGCG ESFMV
//