ID A0A1W2TVY4_ROSNE Unreviewed; 868 AA.
AC A0A1W2TVY4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 02-APR-2025, entry version 25.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=SAMD00023353_9500190 {ECO:0000313|EMBL:GAP92810.2};
OS Rosellinia necatrix (White root-rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Xylariaceae; Rosellinia.
OX NCBI_TaxID=77044 {ECO:0000313|EMBL:GAP92810.2};
RN [1] {ECO:0000313|EMBL:GAP92810.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W97 {ECO:0000313|EMBL:GAP92810.2};
RA Kanematsu S.;
RT "Draft genome sequence of Rosellinia necatrix.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
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DR EMBL; DF977540; GAP92810.2; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W2TVY4; -.
DR STRING; 77044.A0A1W2TVY4; -.
DR OMA; PWFNYET; -.
DR OrthoDB; 9977870at2759; -.
DR Proteomes; UP000054516; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20335; BRcat_RBR; 1.
DR CDD; cd22584; Rcat_RBR_unk; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS51873; TRIAD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054516};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 381..581
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT REGION 1..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 603..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 681..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..54
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..87
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..106
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..131
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..185
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..231
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..291
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..362
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..380
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 626..640
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..698
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 868 AA; 97319 MW; 3CDF80F753D63C75 CRC64;
MADSQYVAGK RRYGRGRQTA ASENHDWEPR RGESRHSLPY RIRQPEIQRP DRRNPKYSSR
PSRTSEDLAH TGAMPAPMRM LPRPATPKSR GRRQYDEDED DDDDDSERER LRGRLRSRSR
APSGPASRPA SKSAWGGKSR ATSGVASRAP SGVTSRAKSG AKSRPVSRDS QSTDSSPFPT
PTRSSFVQLH PAPSAPSPGA STESSSEDSD DESSGSTQDY RMHTRTLKER MNMTPDSEPA
PNPAARSRSR HKSRERIVPE IESPTEDSDD QARRPRLILK KRSLSRPRLA HQSRSPSRAP
RHRRQTDRHG EERPSLSPKR GSKKYHHSDF AQPRETPFSR SRATSASRVK SAQSAGSSSK
PSLGNFFPTS GPSQPYDQGS KSHTCVACKD RLPAEDLAKL KCGHRWCEDC LKRRFELSIE
DVQNMPPRCC TSDIIPIKYV TDLFGDDFKK TWNEKFAKFS ARGRIYCPRP KCREPIRPTD
YRHHSNGRTS ATCRKCEAKI CGLCYNKWHE SKRCPGDADT AQFLKVAKEA GWKRCFNCQA
MVELKEGCNH MTCRCGAQFC MICGLKWKGC ECPWFSYDLE EEDEFGHVQI PIPMVSRERL
GGAGGVPRGL RPDLGYAPEP RHHRGHRDDD RTRRLQHVEI DVDDDEEDDD HDDYIDGMGG
VVGAGDTGGH FMGDSYRRRS HSTAVPQAPS APLAAPSVAH ERTKSGTNYV SGVNKARGVR
GSSMERRLAD RFEQRQSFNP HHRSFGQPGP PLTAPPLTAP PLGMAPLPHQ PPMVPSPISR
RHTIDNDMYD IPFDPRYASH AIPRRSTSHA YVDDFAVHAP LGRRRYRQME PPRPSELAGL
TGPGGGMNRV FEWANHVETF PPDNQTVA
//
