ID A0A1Y0CE13_9MYCO Unreviewed; 197 AA.
AC A0A1Y0CE13;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 08-OCT-2025, entry version 35.
DE SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:ART73481.1};
GN ORFNames=BTO20_07640 {ECO:0000313|EMBL:ART73481.1};
OS Mycobacterium dioxanotrophicus.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Mycobacteriaceae; Mycobacterium.
OX NCBI_TaxID=482462 {ECO:0000313|EMBL:ART73481.1, ECO:0000313|Proteomes:UP000195331};
RN [1] {ECO:0000313|EMBL:ART73481.1, ECO:0000313|Proteomes:UP000195331}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PH-06 {ECO:0000313|EMBL:ART73481.1,
RC ECO:0000313|Proteomes:UP000195331};
RA He Y.;
RT "Whole Genome Sequence of 1,4-Dioxane Degrading Bacterium Mycobacterium
RT dioxanotrophicus PH-06.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
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DR EMBL; CP020809; ART73481.1; -; Genomic_DNA.
DR RefSeq; WP_087081754.1; NZ_CP020809.1.
DR AlphaFoldDB; A0A1Y0CE13; -.
DR KEGG; mdx:BTO20_07640; -.
DR OrthoDB; 70491at2; -.
DR Proteomes; UP000195331; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:TreeGrafter.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:TreeGrafter.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProtKB-ARBA.
DR FunFam; 1.10.10.60:FF:000141; TetR family transcriptional regulator; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR054129; DesT_TetR_C.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeodomain-like_sf.
DR InterPro; IPR050109; HTH-type_TetR-like_transc_reg.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF227; TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)-RELATED; 1.
DR Pfam; PF21943; TetR_C_46; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Reference proteome {ECO:0000313|Proteomes:UP000195331};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..64
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 27..46
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 197 AA; 21742 MW; FB3E5DFFA1D20E96 CRC64;
MTGSERRQQL IEIAKSLFAE RGYDGTSIEE IAQRANVSKP VVYEHFGGKE GLYAVVVDRE
MSALLEGITS SLTRNRSRVR VERVALALLT YVEEHTDGFR ILIRDSPAAI TSGTYATLLN
DAVNQVSSIL AGDFSRRGLD PELAPLYAQA LVGSVSMTAQ WWLDVREPPK EVVAAHVVNL
AWNGLTHLEP DPVLHEE
//
