ID A0A1Y1N4J1_PHOPY Unreviewed; 395 AA.
AC A0A1Y1N4J1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 18-JUN-2025, entry version 27.
DE RecName: Full=Proteasomal ubiquitin receptor ADRM1 homolog {ECO:0000256|ARBA:ARBA00070663};
GN ORFNames=PPYR_02232 {ECO:0000313|EMBL:KAB0805262.1};
OS Photinus pyralis (Common eastern firefly) (Lampyris pyralis).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Elateriformia; Elateroidea;
OC Lampyridae; Lampyrinae; Photinus.
OX NCBI_TaxID=7054 {ECO:0000313|EMBL:JAV91790.1};
RN [1] {ECO:0000313|EMBL:JAV91790.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=28004739; DOI=10.1038/srep38556;
RA Al-Wathiqui N., Fallon T.R., South A., Weng J.K., Lewis S.M.;
RT "Molecular characterization of firefly nuptial gifts: a multi-omics
RT approach sheds light on postcopulatory sexual selection.";
RL Sci. Rep. 6:38556-38556(2016).
RN [2] {ECO:0000313|EMBL:KAB0805262.1, ECO:0000313|Proteomes:UP000327044}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1611_PpyrPB1 {ECO:0000313|EMBL:KAB0805262.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KAB0805262.1};
RX PubMed=30324905;
RA Fallon T.R., Lower S.E., Chang C.H., Bessho-Uehara M., Martin G.J.,
RA Bewick A.J., Behringer M., Debat H.J., Wong I., Day J.C., Suvorov A.,
RA Silva C.J., Stanger-Hall K.F., Hall D.W., Schmitz R.J., Nelson D.R.,
RA Lewis S.M., Shigenobu S., Bybee S.M., Larracuente A.M., Oba Y., Weng J.K.;
RT "Firefly genomes illuminate parallel origins of bioluminescence in
RT beetles.";
RL Elife 7:e36495-e36495(2018).
RN [3] {ECO:0000313|EMBL:KAB0805262.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=1611_PpyrPB1 {ECO:0000313|EMBL:KAB0805262.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KAB0805262.1};
RG Photinus pyralis genome working group;
RA Fallon T.R., Sander Lower S.E., Weng J.-K.;
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May function as a proteasomal ubiquitin receptor. May promote
CC the deubiquitinating activity associated with the 26S proteasome.
CC {ECO:0000256|ARBA:ARBA00054744}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
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DR EMBL; GEZM01015283; JAV91790.1; -; Transcribed_RNA.
DR EMBL; GEZM01015280; JAV91792.1; -; Transcribed_RNA.
DR EMBL; GEZM01015279; JAV91793.1; -; Transcribed_RNA.
DR EMBL; GEZM01015278; JAV91794.1; -; Transcribed_RNA.
DR EMBL; VVIM01000001; KAB0805262.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y1N4J1; -.
DR FunCoup; A0A1Y1N4J1; 1351.
DR InParanoid; A0A1Y1N4J1; -.
DR OrthoDB; 340431at2759; -.
DR Proteomes; UP000327044; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000327044}.
FT DOMAIN 19..132
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 257..369
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 127..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..147
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..229
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..375
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..395
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 395 AA; 41922 MW; FDB3A9FDFB640748 CRC64;
MPSGGALFGS SAGGPGSTGG IKHLIEMRAG KMNQKGRMVV PDVRKGLLYV YQSEDSLMHF
CWQDRTTGIV EDDLIIFPDD CEYVKVPQCT TGRVYLLKFK SSHRRFFFWL QEPRTDKDED
NCKRINEILN NPSGNVSSGG SSDQDLQSLL NNMSQSQLMQ LFGGGVGQIG GLSSLLGTMN
RPSTGGTRSS GATPALTHRT TSSTPSATTT STTAPTGTTT TTTAETPTSQ PVTQSASSIN
SPIQLTDLQN FLQGIAPTAS TDPQSVDLST ALTGDALSGL LSNSDAMNQL ETHLPAIGGT
TEDQLRSTLA SPQFQQAVQQ FSSALESGQL APIVSQLAVS SEAVAAASHG NMADFVKALE
KGGSDESSKK DEKKENKNKK KNNPDDDDDE GMQLD
//
