ID A0A226E4Y0_FOLCA Unreviewed; 507 AA.
AC A0A226E4Y0;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 18-JUN-2025, entry version 28.
DE SubName: Full=WD repeat-containing protein 46 {ECO:0000313|EMBL:OXA52765.1};
GN ORFNames=Fcan01_12554 {ECO:0000313|EMBL:OXA52765.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA52765.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA52765.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA52765.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA52765.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA52765.1}.
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DR EMBL; LNIX01000006; OXA52765.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226E4Y0; -.
DR STRING; 158441.A0A226E4Y0; -.
DR OMA; EFLPYHW; -.
DR OrthoDB; 10251154at2759; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0030686; C:90S preribosome; IEA:TreeGrafter.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:TreeGrafter.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:TreeGrafter.
DR FunFam; 2.130.10.10:FF:000378; U3 small nucleolar RNA-associated protein 7; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR012952; BING4_C_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR040315; WDR46/Utp7.
DR PANTHER; PTHR14085:SF3; WD REPEAT-CONTAINING PROTEIN 46; 1.
DR PANTHER; PTHR14085; WD-REPEAT PROTEIN BING4; 1.
DR Pfam; PF08149; BING4CT; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM01033; BING4CT; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 261..296
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 340..418
FT /note="BING4 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01033"
FT REGION 469..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..488
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 507 AA; 56218 MW; 4DFA0CCF3A4177FC CRC64;
MSVPEDPLVV STAVGKHSRG KGLSSNLDVK MGIRKTKILR KEAKIVSGVE RAARSEILLV
EDSGGIEVDE GEHTLQLKQF DITKKIDIAS ATKGFHLSLD EFGPYKLRYT NNGRYLVLGG
RKGHIAAFDW VTKNLMCEIG VRESVHDVVW LHNENMFAAA QKEWTYIYDN QGIEIHCLKS
MDRVINLDFL PYHFLLVGGH QSGYLSWVDV SIGKIVSQFN ARSGPVAIMT TNPANAVVHC
GHTNGTVSLW APTVRKSLAS ILCHGCPLSA VAVDNVGRLM ATSGRDGSMR IWDLRNSYTP
LLSVKVGISS LLQFSQRGLL AMATSTDAMI FSEVSHKTKP YLKHVANSQI SSMQFCPFED
VLGVGTNRGF DSVIVPGAGE PNFDALERNP YQSKGQRCEA EIKGLLEKIQ PELITLDNNI
LGEVDTHAVS SSLDKKPNYV KKKDIQLAHR KKRKNAKLPK IKEGLRTELN LKLAKSEHQT
KKREEQSKKT IQMSDDDPLS RFAKKSK
//
