ID   A0A238BRM0_9BILA        Unreviewed;       483 AA.
AC   A0A238BRM0;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   18-JUN-2025, entry version 19.
DE   RecName: Full=Glycerate kinase {ECO:0000256|ARBA:ARBA00020720};
DE            EC=2.7.1.31 {ECO:0000256|ARBA:ARBA00012101};
GN   ORFNames=X798_05116 {ECO:0000313|EMBL:OZC07902.1};
OS   Onchocerca flexuosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=387005 {ECO:0000313|EMBL:OZC07902.1, ECO:0000313|Proteomes:UP000242913};
RN   [1] {ECO:0000313|EMBL:OZC07902.1, ECO:0000313|Proteomes:UP000242913}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Red Deer {ECO:0000313|EMBL:OZC07902.1};
RA   Mitreva M.;
RT   "Draft genome of the nematode, Onchocerca flexuosa.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H(+);
CC         Xref=Rhea:RHEA:23516, ChEBI:CHEBI:15378, ChEBI:CHEBI:16659,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58272, ChEBI:CHEBI:456216;
CC         EC=2.7.1.31; Evidence={ECO:0000256|ARBA:ARBA00000694};
CC   -!- SIMILARITY: Belongs to the glycerate kinase type-2 family.
CC       {ECO:0000256|ARBA:ARBA00005393}.
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DR   EMBL; KZ270019; OZC07902.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238BRM0; -.
DR   OrthoDB; 44918at2759; -.
DR   Proteomes; UP000242913; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR   GO; GO:0008887; F:glycerate kinase activity; IEA:InterPro.
DR   FunFam; 3.40.50.10180:FF:000001; Glycerate kinase; 1.
DR   Gene3D; 3.40.50.10180; Glycerate kinase, MOFRL-like N-terminal domain; 1.
DR   Gene3D; 3.40.1480.10; MOFRL domain; 1.
DR   InterPro; IPR037035; GK-like_C_sf.
DR   InterPro; IPR038614; GK_N_sf.
DR   InterPro; IPR007835; MOFRL.
DR   InterPro; IPR025286; MOFRL_assoc_dom.
DR   InterPro; IPR039760; MOFRL_protein.
DR   PANTHER; PTHR12227; GLYCERATE KINASE; 1.
DR   PANTHER; PTHR12227:SF0; GLYCERATE KINASE; 1.
DR   Pfam; PF13660; DUF4147; 1.
DR   Pfam; PF05161; MOFRL; 1.
DR   SUPFAM; SSF82544; GckA/TtuD-like; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242913};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          23..262
FT                   /note="MOFRL-associated"
FT                   /evidence="ECO:0000259|Pfam:PF13660"
FT   DOMAIN          355..474
FT                   /note="MOFRL"
FT                   /evidence="ECO:0000259|Pfam:PF05161"
SQ   SEQUENCE   483 AA;  52170 MW;  173A7C553665B0A5 CRC64;
     MNLNPFNLDP CIAMSELRDL CFHAFQVAVD AAQPYQHVRD TLRLTNGVIK VGQRIYQINH
     NVHLAAFGKA ALNMVHGAED ALDGHIIEGI ASVPRGTLQK LKNMNLRTKF LEGATNNLPD
     EDACNNARLI EEMAERLQTS NDIFLVLISG GGSALLSAPI SSISLDDKRK TVNAMTLRGA
     EIKQLNTVRK ALSRLKGGKL AQIAHPAKTL GIIVSDIVGD PLEFIASGPT VITSPDNPDP
     ITVLKELNAW NAISSSVQDA LEKSHGMESV QDVDVHNTIV LNNKIILSSL GEVLKKDGYQ
     CHVVSNVVEE DADSFGFQLA NVINAVIAGK PLNEALQSMN LASANKTASF GDKTALLFGG
     ECTVTIKGSG NGGRNQQIVL AALSKLLEQF DFGQEKVEFA LMSAGTDGQD GPTDAAGAVL
     TSNDMRHIRE AGSKWEKMVI DDYLNNNDSY NFWKKFNNGK SHIIFGPSGT NVMDVQVLLF
     NIK
//