ID   A0A238C600_9BILA        Unreviewed;       255 AA.
AC   A0A238C600;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   05-FEB-2025, entry version 16.
DE   RecName: Full=NFU1 iron-sulfur cluster scaffold homolog, mitochondrial {ECO:0000256|ARBA:ARBA00018782};
GN   ORFNames=X798_00338 {ECO:0000313|EMBL:OZC12706.1};
OS   Onchocerca flexuosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=387005 {ECO:0000313|EMBL:OZC12706.1, ECO:0000313|Proteomes:UP000242913};
RN   [1] {ECO:0000313|EMBL:OZC12706.1, ECO:0000313|Proteomes:UP000242913}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Red Deer {ECO:0000313|EMBL:OZC12706.1};
RA   Mitreva M.;
RT   "Draft genome of the nematode, Onchocerca flexuosa.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Molecular scaffold for [Fe-S] cluster assembly of
CC       mitochondrial iron-sulfur proteins. {ECO:0000256|ARBA:ARBA00002175}.
CC   -!- SIMILARITY: Belongs to the NifU family.
CC       {ECO:0000256|ARBA:ARBA00006420}.
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DR   EMBL; KZ269977; OZC12706.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238C600; -.
DR   OrthoDB; 565552at2759; -.
DR   Proteomes; UP000242913; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:TreeGrafter.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR   FunFam; 3.30.300.130:FF:000001; NFU1 iron-sulfur cluster scaffold; 1.
DR   FunFam; 3.30.1370.70:FF:000001; NifU-like protein 4, mitochondrial; 1.
DR   Gene3D; 3.30.300.130; Fe-S cluster assembly (FSCA); 1.
DR   Gene3D; 3.30.1370.70; Scaffold protein Nfu/NifU, N-terminal domain; 1.
DR   InterPro; IPR034904; FSCA_dom_sf.
DR   InterPro; IPR014824; Nfu/NifU_N.
DR   InterPro; IPR036498; Nfu/NifU_N_sf.
DR   InterPro; IPR035433; NFU1-like.
DR   InterPro; IPR001075; NIF_FeS_clus_asmbl_NifU_C.
DR   PANTHER; PTHR11178; IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED; 1.
DR   PANTHER; PTHR11178:SF1; NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL; 1.
DR   Pfam; PF08712; Nfu_N; 1.
DR   Pfam; PF01106; NifU; 1.
DR   PIRSF; PIRSF036773; HIRIP5; 1.
DR   SMART; SM00932; Nfu_N; 1.
DR   SUPFAM; SSF117916; Fe-S cluster assembly (FSCA) domain-like; 1.
DR   SUPFAM; SSF110836; Hypothetical protein SAV1430; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000242913}.
FT   DOMAIN          38..127
FT                   /note="Scaffold protein Nfu/NifU N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00932"
SQ   SEQUENCE   255 AA;  28871 MW;  755392941D8EBBDC CRC64;
     MFYEIWNHRL FQMARKSQYL LTVTPSTSLI RPVRNMFIQV QETPNPATLK FIPGKTIMGK
     GKGTLNFTNF LSAKRSPLAM QLFRVSGVKS IFFGENYVTI TKENEIDDWA LLKPEIFAVL
     MDYLQSEKPI VNEGDMPKNP EDTEIHPEDS DTVAMIKELL ECRIKPMVQE DGGDVIYKGF
     HDGVVHLKMQ GSCTGCPSSS VTLQSGIKNM LQFYVPEVKD VIEVKDEADD VLDSAFDDLM
     GKIKVKPNPN EQNKE
//