ID   A0A238XX62_HALVU        Unreviewed;       155 AA.
AC   A0A238XX62;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   02-APR-2025, entry version 21.
DE   SubName: Full=Multisubunit sodium/proton antiporter, MrpB subunit {ECO:0000313|EMBL:SNR63585.1};
GN   ORFNames=SAMN06264855_12514 {ECO:0000313|EMBL:SNR63585.1};
OS   Halorubrum vacuolatum (Natronobacterium vacuolatum).
OC   Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC   Halobacteria; Halobacteriales; Haloferacaceae; Halorubrum.
OX   NCBI_TaxID=63740 {ECO:0000313|EMBL:SNR63585.1, ECO:0000313|Proteomes:UP000198397};
RN   [1] {ECO:0000313|EMBL:SNR63585.1, ECO:0000313|Proteomes:UP000198397}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 8800 {ECO:0000313|EMBL:SNR63585.1,
RC   ECO:0000313|Proteomes:UP000198397};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
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DR   EMBL; FZNQ01000025; SNR63585.1; -; Genomic_DNA.
DR   RefSeq; WP_089385824.1; NZ_FZNQ01000025.1.
DR   AlphaFoldDB; A0A238XX62; -.
DR   OrthoDB; 19265at2157; -.
DR   Proteomes; UP000198397; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR050622; CPA3_antiporter_subunitB.
DR   InterPro; IPR007182; MnhB.
DR   PANTHER; PTHR33932; NA(+)/H(+) ANTIPORTER SUBUNIT B; 1.
DR   PANTHER; PTHR33932:SF4; NA(+)_H(+) ANTIPORTER SUBUNIT B; 1.
DR   Pfam; PF04039; MnhB; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198397};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          22..138
FT                   /note="Na+/H+ antiporter MnhB subunit-related protein"
FT                   /evidence="ECO:0000259|Pfam:PF04039"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   155 AA;  15903 MW;  A9093D156841462C CRC64;
     MSDSEPVTRE PKGESDVSES PVVRTASRTV TPFVVAFGVY LTLFGTSLPG GAFQGGVVMA
     SVVVLVAMAF GFAPTQKWLD ERALAGLFVL GAAIFGAVAF GAVALGGDVL ELFVFPLSVE
     NMVKLVEVAI AALVAGVIIG LYVWLADGIH GGKSA
//