ID A0A242JZ35_9ENTE Unreviewed; 281 AA.
AC A0A242JZ35;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 18-JUN-2025, entry version 19.
DE SubName: Full=PTS system mannose/fructose/sorbose-specific IIC component {ECO:0000313|EMBL:OTP10578.1};
GN ORFNames=A5888_003174 {ECO:0000313|EMBL:WYJ91406.1}, A5888_003876
GN {ECO:0000313|EMBL:OTP10578.1};
OS Candidatus Enterococcus clewellii.
OC Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1834193 {ECO:0000313|EMBL:OTP10578.1};
RN [1] {ECO:0000313|EMBL:OTP10578.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9E7_DIV0242 {ECO:0000313|EMBL:OTP10578.1};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genomic Center for Infectious Diseases;
RA Earl A., Manson A., Schwartman J., Gilmore M., Abouelleil A., Cao P.,
RA Chapman S., Cusick C., Shea T., Young S., Neafsey D., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Enterococcus sp. 9E7_DIV0242.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:WYJ91406.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=9E7_DIV0242 {ECO:0000313|EMBL:WYJ91406.1};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genomic Center for Infectious Diseases;
RA Earl A., Manson A., Schwartman J., Gilmore M., Abouelleil A., Cao P.,
RA Chapman S., Cusick C., Shea T., Young S., Neafsey D., Nusbaum C.,
RA Birren B.;
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:WYJ91406.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=9E7_DIV0242 {ECO:0000313|EMBL:WYJ91406.1};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Microbial Omics Core;
RG The Broad Institute Genomic Center for Infectious Diseases;
RA Earl A., Manson A., Gilmore M., Schwartman J., Shea T., Abouelleil A.,
RA Cao P., Chapman S., Cusick C., Young S., Neafsey D., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus sp. DIV0242b.";
RL Submitted (MAR-2024) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
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DR EMBL; NGMM01000008; OTP10578.1; -; Genomic_DNA.
DR EMBL; CP147247; WYJ91406.1; -; Genomic_DNA.
DR RefSeq; WP_086350857.1; NZ_CP147247.1.
DR AlphaFoldDB; A0A242JZ35; -.
DR OrthoDB; 9815089at2; -.
DR Proteomes; UP000195141; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR InterPro; IPR050303; GatZ_KbaZ_carbometab.
DR InterPro; IPR004700; PTS_IIC_man.
DR PANTHER; PTHR32502; N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED; 1.
DR PANTHER; PTHR32502:SF8; N-ACETYLGALACTOSAMINE PERMEASE IIC COMPONENT 1; 1.
DR Pfam; PF03609; EII-Sor; 1.
DR PROSITE; PS51106; PTS_EIIC_TYPE_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000195141};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 37..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 260..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..281
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 281 AA; 29638 MW; A04B67E209C1FB0C CRC64;
METLSVLQSL LIALWTAAVM SRWLGGGATL TLRFSPLMTG LVVGIIMGNV PQAMIVTASL
QMIYMGVFSP GGSMPAEPSI AAAIAVPVAL LGDLSPEAAI AVAVPVGLLG SYLYQFRFFI
NTFLGKYTDK AVEDLNAKAI ARSVIVYPTI ASFLLFVPLV FVSLYFGAPV IADVITALEG
TVVIHVLEVV GGGLAAIGIA TTIYVIGRKD YMVFFFLAYF MSIVMKSLEV TMVTYAIFGI
IIALIFVQSQ KGKNVPAASN GGGNAGATFD GDDDDDYDDG F
//
