ID A0A243WL95_9BACT Unreviewed; 285 AA.
AC A0A243WL95;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 18-JUN-2025, entry version 15.
DE RecName: Full=Sulfur carrier protein FdhD {ECO:0000256|HAMAP-Rule:MF_00187};
GN Name=fdhD {ECO:0000256|HAMAP-Rule:MF_00187};
GN ORFNames=BXP70_02605 {ECO:0000313|EMBL:OUJ76360.1};
OS Hymenobacter crusticola.
OC Bacteria; Pseudomonadati; Bacteroidota; Cytophagia; Cytophagales;
OC Hymenobacteraceae; Hymenobacter.
OX NCBI_TaxID=1770526 {ECO:0000313|EMBL:OUJ76360.1, ECO:0000313|Proteomes:UP000194873};
RN [1] {ECO:0000313|EMBL:OUJ76360.1, ECO:0000313|Proteomes:UP000194873}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIMBbqt21 {ECO:0000313|EMBL:OUJ76360.1};
RA Liang Y., Feng F.;
RT "A new Hymenobacter.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC sulfur carrier protein that transfers sulfur from IscS to the
CC molybdenum cofactor prior to its insertion into FDH.
CC {ECO:0000256|HAMAP-Rule:MF_00187}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00187}.
CC -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000256|HAMAP-
CC Rule:MF_00187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUJ76360.1}.
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DR EMBL; MTSE01000001; OUJ76360.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A243WL95; -.
DR Proteomes; UP000194873; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.20.10; -; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR HAMAP; MF_00187; FdhD; 1.
DR InterPro; IPR016193; Cytidine_deaminase-like.
DR InterPro; IPR003786; FdhD.
DR NCBIfam; TIGR00129; fdhD_narQ; 1.
DR NCBIfam; NF001943; PRK00724.1-2; 1.
DR PANTHER; PTHR30592; FORMATE DEHYDROGENASE; 1.
DR PANTHER; PTHR30592:SF1; SULFUR CARRIER PROTEIN FDHD; 1.
DR Pfam; PF02634; FdhD-NarQ; 1.
DR PIRSF; PIRSF015626; FdhD; 1.
DR SUPFAM; SSF53927; Cytidine deaminase-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00187};
KW Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150,
KW ECO:0000256|HAMAP-Rule:MF_00187};
KW Reference proteome {ECO:0000313|Proteomes:UP000194873};
KW Transferase {ECO:0000313|EMBL:OUJ76360.1}.
FT ACT_SITE 123
FT /note="Cysteine persulfide intermediate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00187"
FT BINDING 265..270
FT /ligand="Mo-bis(molybdopterin guanine dinucleotide)"
FT /ligand_id="ChEBI:CHEBI:60539"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00187"
SQ SEQUENCE 285 AA; 30419 MW; 6C31CE4B077875B1 CRC64;
MPAASYDYAT VQRVAGGQVI TESDLVAAEE PLEIRLGFGP AGQREHRTLS VTMRTPGHDF
ELAAGFLLTE GIIQRRQDLT GVIYCPDVEK PEERENVVRA ELASSVEVSM PRLERHFYTS
SSCGVCGKTS IDAVQAASCP VLPTDGPFVA AELIHELPAR QRAAQELFEQ TGGLHAAALF
SPTGELLLLR EDVGRHNALD KVIGAALLQE WLPLHNSILL VSGRASFELV QKAAVAGIPV
MAAVGAPSSL AVQAAAGFGM TLLGFVRQQR YNVYSGAWRI TGAGS
//
