ID A0A251UB94_HELAN Unreviewed; 609 AA.
AC A0A251UB94;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 08-OCT-2025, entry version 26.
DE SubName: Full=Phosphatidylinositol-glycan biosynthesis class S protein {ECO:0000313|EMBL:KAF5798111.1};
DE SubName: Full=Putative GPI transamidase component PIG-S-related protein {ECO:0000313|EMBL:OTG20126.1};
GN ORFNames=HannXRQ_Chr07g0189551 {ECO:0000313|EMBL:OTG20126.1},
GN HanXRQr2_Chr07g0288931 {ECO:0000313|EMBL:KAF5798111.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTG20126.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5798111.1, ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5798111.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:OTG20126.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaves {ECO:0000313|EMBL:OTG20126.1};
RA Langlade N., Munos S.;
RT "Sunflower complete genome.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAF5798111.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5798111.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}.
CC -!- SIMILARITY: Belongs to the PIGS family.
CC {ECO:0000256|ARBA:ARBA00005316}.
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DR EMBL; MNCJ02000322; KAF5798111.1; -; Genomic_DNA.
DR EMBL; CM007896; OTG20126.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251UB94; -.
DR FunCoup; A0A251UB94; 5075.
DR STRING; 4232.A0A251UB94; -.
DR Gramene; mRNA:HanXRQr2_Chr07g0288931; mRNA:HanXRQr2_Chr07g0288931; HanXRQr2_Chr07g0288931.
DR InParanoid; A0A251UB94; -.
DR OMA; VGDIPFF; -.
DR OrthoDB; 28748at2759; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000215914; Chromosome 7.
DR GO; GO:0042765; C:GPI-anchor transamidase complex; IBA:GO_Central.
DR GO; GO:0016255; P:attachment of GPI anchor to protein; IBA:GO_Central.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR019540; PtdIno-glycan_biosynth_class_S.
DR PANTHER; PTHR21072; GPI TRANSAMIDASE COMPONENT PIG-S; 1.
DR PANTHER; PTHR21072:SF13; GPI TRANSAMIDASE COMPONENT PIG-S; 1.
DR Pfam; PF10510; PIG-S; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 565..584
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 68251 MW; 315ACDAC8A1FA485 CRC64;
MAEISETMGT ESSPPEETTN EHSKSSNFDD KTMRKTKPGL KRLILTLTVL FSFLLGLPWL
LKSIEIYRSP LPFRDIDSLA TAIDSKPLVF PCRFHLVFVN FDHSSSIKPK VDNLGFLVSS
YMSEYAVSNS YCGTCDGNYT VSVSLDTGDN CVEYEDADKR ILWKCGALSE FNFDQSDEAF
DEYLQDTVGG SRVYTVVVVN TDQGDRLRAV VGKYRHAWVV GRVGEMNLVA EMAAEMFVKV
FVSGAKDEGS IQGEFMPVGA DGKIVLSFNL LNADPRDWVY DWDFKEVDEK LLAPTLEALA
PIANISVESQ VLYHTPKSSY SYWDDEQESH IFSTKDLPFF VNSNEWHLDT SIAAGGRSKI
LQFVVYVPSA NECPLRLQLP TGEISVTNGF ISPTWGGVVV FNPPNCLENA NSMHPLRRKL
SSQELNQIFE VFMGQLRQLF GLKSTGFYKG SSGTSVLLAS ERGFTEWELD ALARQHACYN
LQQCGTTLGS LSRLVQSLPR MIIKDEIGKQ VKFSLEAAKL AQHNASQGIC DASAVSSRHA
RSLAEDAFFH PSVMSISYYS FEHMFAVYSP FFLPLSLHVI LAVVREIKRY KQESRKYAAW
EALRKQHSD
//
