ID A0A261QIW0_9BACI Unreviewed; 333 AA.
AC A0A261QIW0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 18-JUN-2025, entry version 20.
DE RecName: Full=DNA polymerase III subunit delta' {ECO:0000256|ARBA:ARBA00014363};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=CEW92_08215 {ECO:0000313|EMBL:OZI12140.1};
OS Bacillaceae bacterium SAS-127.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae.
OX NCBI_TaxID=2015203 {ECO:0000313|EMBL:OZI12140.1, ECO:0000313|Proteomes:UP000217062};
RN [1] {ECO:0000313|EMBL:OZI12140.1, ECO:0000313|Proteomes:UP000217062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAS-127 {ECO:0000313|EMBL:OZI12140.1,
RC ECO:0000313|Proteomes:UP000217062};
RA Verma A., Pal Y., Krishnamurthi S.;
RT "Indiibacillus sp. (SAS-127) genome sequencing.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) +
CC diphosphate; Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339, Rhea:RHEA-
CC COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, ChEBI:CHEBI:173112;
CC EC=2.7.7.7; Evidence={ECO:0000256|ARBA:ARBA00049244};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZI12140.1}.
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DR EMBL; NKXN01000033; OZI12140.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A261QIW0; -.
DR OrthoDB; 9810148at2; -.
DR Proteomes; UP000217062; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:TreeGrafter.
DR FunFam; 3.40.50.300:FF:001255; DNA polymerase III subunit delta; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004622; DNA_pol_HolB.
DR InterPro; IPR015199; DNA_pol_III_delta_C.
DR InterPro; IPR050238; DNA_Rep/Repair_Clamp_Loader.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00678; holB; 1.
DR NCBIfam; NF005972; PRK08058.1; 1.
DR PANTHER; PTHR11669:SF8; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR Pfam; PF09115; DNApol3-delta_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000217062};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 245..326
FT /note="DNA polymerase III delta subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09115"
SQ SEQUENCE 333 AA; 37488 MW; 0B702EBDF42AE5AB CRC64;
MSEVWKELNE LQPVVLRMLT NGLEKERVAH AYIFEGDQGT GKKNAALFFA KSLLCEEDGI
MACEVCNSCR RIESGNHPDV HYLEPDGLSI KKQQITFLQQ EFSKTAVEAQ KKIYIIQHAD
KMTASAANSL LKFLEEPSAD TVALLLTEQV QRLLPTIISR CQLLVFKPLP SELLQNKLIE
EEISVPMASL VAKLTNNFQE ALELSHEEWF AQSRTIVLKL YEVLQKNPLE AMVKLQEDFN
GHFKDKQQVN QALDLLLLLF KDLLSLQTGK ETGLAFPDQL ALLKHNALQS SAKSITEQMT
AILEAKRKLD ANMNPQLLME QLVLNLQGGA SFV
//
