ID A0A285LV77_9NOCA Unreviewed; 199 AA.
AC A0A285LV77;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 28-JAN-2026, entry version 29.
DE SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:SNY87576.1};
GN ORFNames=SAMN04244553_4524 {ECO:0000313|EMBL:SNY87576.1};
OS Nocardia amikacinitolerans.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Nocardiaceae; Nocardia.
OX NCBI_TaxID=756689 {ECO:0000313|EMBL:SNY87576.1, ECO:0000313|Proteomes:UP000219565};
RN [1] {ECO:0000313|EMBL:SNY87576.1, ECO:0000313|Proteomes:UP000219565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45537 {ECO:0000313|EMBL:SNY87576.1,
RC ECO:0000313|Proteomes:UP000219565};
RA Ehlers B., Leendertz F.H.;
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; OBEG01000004; SNY87576.1; -; Genomic_DNA.
DR RefSeq; WP_067787041.1; NZ_JAMTCV010000003.1.
DR AlphaFoldDB; A0A285LV77; -.
DR STRING; 1379680.GCA_001612615_03844; -.
DR OrthoDB; 3767959at2; -.
DR Proteomes; UP000219565; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:TreeGrafter.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:TreeGrafter.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProtKB-ARBA.
DR FunFam; 1.10.10.60:FF:000141; TetR family transcriptional regulator; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR054129; DesT_TetR_C.
DR InterPro; IPR009057; Homeodomain-like_sf.
DR InterPro; IPR050109; HTH-type_TetR-like_transc_reg.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF158; POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY); 1.
DR Pfam; PF21943; TetR_C_46; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Reference proteome {ECO:0000313|Proteomes:UP000219565};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 11..71
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 34..53
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 199 AA; 21869 MW; 1C9846B886A4A814 CRC64;
MAGGTKRLPR AVREQQMLDA AVEVFARKGF HDTSMDAIAA EAKISKPMLY LYYGSKDELF
RACIQREGMR FIEAVAPAGN PLLTPHEQVR TALEGFLGFV DRNRKSWQVL YRQAIGQQAF
ASEIDNARER VIELTAKLLE SSAKHAEPGT NFDVVAVAVI GAGEAIADRL ASGRIEVAEA
VDLLDDLAWR GLAGRKKPE
//
