ID A0A287AFT5_PIG Unreviewed; 1317 AA.
AC A0A287AFT5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 3.
DT 28-JAN-2026, entry version 46.
DE SubName: Full=Collagen type XV alpha 1 chain {ECO:0000313|Ensembl:ENSSSCP00000042716.3};
GN Name=COL15A1 {ECO:0000313|Ensembl:ENSSSCP00000042716.3,
GN ECO:0000313|VGNC:VGNC:86866};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000042716.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000042716.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000042716.3};
RX PubMed=32543654;
RA Warr A., Affara N., Aken B., Beiki H., Bickhart D.M., Billis K., Chow W.,
RA Eory L., Finlayson H.A., Flicek P., Giron C.G., Griffin D.K., Hall R.,
RA Hannum G., Hourlier T., Howe K., Hume D.A., Izuogu O., Kim K., Koren S.,
RA Liu H., Manchanda N., Martin F.J., Nonneman D.J., O'Connor R.E.,
RA Phillippy A.M., Rohrer G.A., Rosen B.D., Rund L.A., Sargent C.A.,
RA Schook L.B., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R.,
RA Tseng E., Tuggle C.K., Watson M., Smith T.P.L., Archibald A.L.;
RT "An improved pig reference genome sequence to enable pig genetics and
RT genomics research.";
RL Gigascience 9:giaa051-giaa051(2020).
RN [3] {ECO:0000313|Ensembl:ENSSSCP00000042716.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [4] {ECO:0000313|Ensembl:ENSSSCP00000042716.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
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DR Ensembl; ENSSSCT00000042391.3; ENSSSCP00000042716.3; ENSSSCG00000005380.5.
DR VGNC; VGNC:86866; COL15A1.
DR eggNOG; KOG3546; Eukaryota.
DR GeneTree; ENSGT00940000158302; -.
DR Proteomes; UP000008227; Chromosome 1.
DR Bgee; ENSSSCG00000005380; Expressed in subcutaneous adipose tissue and 38 other cell types or tissues.
DR ExpressionAtlas; A0A287AFT5; baseline and differential.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR CDD; cd00247; Endostatin-like; 1.
DR CDD; cd00110; LamG; 1.
DR FunFam; 3.40.1620.70:FF:000002; Collagen alpha 1 (XV) chain; 1.
DR FunFam; 2.60.120.200:FF:000039; Collagen XV alpha 1 chain; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF1109; COLLAGEN ALPHA-4(IV) CHAIN-LIKE; 1.
DR Pfam; PF01391; Collagen; 2.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR SMART; SM00282; LamG; 1.
DR SMART; SM00210; TSPN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 1: Evidence at protein level;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A287AFT5};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1317
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5036449734"
FT DOMAIN 35..223
FT /note="Thrombospondin-like N-terminal"
FT /evidence="ECO:0000259|SMART:SM00210"
FT DOMAIN 84..222
FT /note="Laminin G"
FT /evidence="ECO:0000259|SMART:SM00282"
FT REGION 218..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 371..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 494..773
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 802..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 955..980
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 992..1089
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..535
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 561..571
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..607
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..673
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 694..708
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 743..757
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 838..851
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 872..885
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 896..905
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 994..1007
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1012..1026
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1037..1069
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1079..1088
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1317 AA; 134229 MW; 88E52DBA3298E93D CRC64;
RDAQCWRLLL LLSISALLPA VTRTRSATEL ASQGHLDLTE LIGVPLPSSV SFVTGYGGFP
AYSFGPGANV GRPARTLIPP TFFRDFAISV TVKPSSARGG VLFAITDAFQ KVIYLGLRLS
AVEDGRQRVI LYYTEPGSQV SHEAASFPVP VMTHRWNRFA VVVQGEEASL LVECEEQGHV
SFPRSSQALA FEPSAGIFVG NAGATGLERF TGSIQQLTVH SDPRTPEELC EAEESSASGE
ASGLQETDGV AEMVEAVTYT QAPSEPAEVE PINMPPTPSP LSEDAELSGE PVPEGTQGTT
NLSAFPHSSP EQGSGEILND TLERVHTVDG APVTDTGSGD GAFLHVIEES PHTEEGLAAT
AAAVESEVTI STAGEAETES VPTEGPTLSM STKDPGEEVT LGPDDEEGSA VTAAEEAEVL
VSSPGEAEAG SVPTGELTLS MSTQDPGEGG PVHEESLTTA VTAKAPLSTF EEEASRVPTD
GLAPLIPTVA PEQVFTSGPG DDDLAAAATE EPLISSGAEE LSGVPPEGPP LPLPTVAPER
GGAPGEEGEG LPGPPPPTRP AGPTAGAEAE GSSLGWGLDI GSGSGDPVRS EELLRGPPGP
PGPPGLPGIP GRPGTDVFVG PPGSPGEDGP AGEPGPPGPE GKPGLDGASG LPGMKGEKGA
RGPDGSVGEK GDPGSRGLPG PPGKNGQVGT PGVMGPPGPP GPPGPPGPGC AMGQGFEDTE
GSGSIRLLHE PRISGPVASV GPKGEKGDQG PKGERGMDGA SIVGPPGPRG PPGRIEVLSS
SLINITHGFM NLSDIPELVG PPGPRGPKGD TGVPGFPGLK GEQGEKGEPG AILTGDVPLE
RLRGKKGEPG EHGAPGPMGP KGPPGHKGEF GLPGRPGRPG LNGLKGAKGD RGVMMPGPPG
LPGPPGPPGP PGAVINIKGA VFPIPVRPHC KTPVGTTHPG NSELITFHGV KGEKGSWGLP
GSKGEKGDQG AQGPPGPPVD PAYLRHFLNS LKGENGDRGM KGEKGDTYEG FSVSGPPGLP
GSPGLVGQKG ETVIGPQGPP GVPGLPGPPG FGRPGSPGPP GPPGPPGPPA ILGAAVALPG
PPGPPGQPGL PGSRNLVTAF SNMDDMLQKA HLVIEGTFIY LRDSTEFFIR VRDGWKKLQL
GELIPLPADS LPPPALSGNP HQPQLPLTSI SSVNYDRPAL HLVALNTPSS GDLRADFQCF
QQARAAGLLS TYRAFLSSHL QDLSTIVRKA ERYSLPIVNL KGQVLFNNWD SIFSGHGGQF
NTHVPIYSFD GRDVMTDPSW PQKVVWHGSS THGVRLVDQY CEAWRTADVA VMGLAPR
//
