ID A0A2A6CIR4_PRIPA Unreviewed; 1926 AA.
AC A0A2A6CIR4; A0A8R1YAD6;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 28-JAN-2026, entry version 31.
DE SubName: Full=Cle-1 {ECO:0000313|EnsemblMetazoa:PPA06492.1};
GN Name=WBGene00096046 {ECO:0000313|EnsemblMetazoa:PPA06492.1};
OS Pristionchus pacificus (Parasitic nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae;
OC Pristionchus.
OX NCBI_TaxID=54126 {ECO:0000313|EnsemblMetazoa:PPA06492.1, ECO:0000313|Proteomes:UP000005239};
RN [1] {ECO:0000313|Proteomes:UP000005239}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PS312 {ECO:0000313|Proteomes:UP000005239};
RX PubMed=18806794; DOI=10.1038/ng.227;
RA Dieterich C., Clifton S.W., Schuster L.N., Chinwalla A., Delehaunty K.,
RA Dinkelacker I., Fulton L., Fulton R., Godfrey J., Minx P., Mitreva M.,
RA Roeseler W., Tian H., Witte H., Yang S.P., Wilson R.K., Sommer R.J.;
RT "The Pristionchus pacificus genome provides a unique perspective on
RT nematode lifestyle and parasitism.";
RL Nat. Genet. 40:1193-1198(2008).
RN [2] {ECO:0000313|EnsemblMetazoa:PPA06492.1}
RP IDENTIFICATION.
RC STRAIN=PS312 {ECO:0000313|EnsemblMetazoa:PPA06492.1};
RG EnsemblMetazoa;
RL Submitted (JUN-2022) to UniProtKB.
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DR EnsemblMetazoa; PPA06492.1; PPA06492.1; WBGene00096046.
DR Proteomes; UP000005239; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR CDD; cd16983; CID_SCAF8_like; 1.
DR FunFam; 3.40.1620.70:FF:000003; Collagen type XVIII alpha 1; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 1.20.5.320; 6-Phosphogluconate Dehydrogenase, domain 3; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR006569; CID_dom.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR051485; SR-CTD_assoc_factor.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR23140:SF4; PROTEIN CBR-NRD-1; 1.
DR PANTHER; PTHR23140; RNA PROCESSING PROTEIN LD23810P; 1.
DR Pfam; PF04818; CID; 1.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SMART; SM00582; RPR; 1.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00210; TSPN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS51391; CID; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005239};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 333..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1004..1045
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1103..1135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1374..1409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1426..1540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1823..1869
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1162..1201
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 370..383
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..421
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..525
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1012..1023
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1112..1122
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1387..1409
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1434..1500
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1501..1511
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1512..1528
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1835..1847
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1851..1867
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1926 AA; 212046 MW; AE2895981CA148B6 CRC64;
MIYHPWINSW RSLPSSPFIY FFILSLFIPS SLQYANFIDE FPMGLPGDTE TTVDLLVPVE
QTLNSDPRVF RARGIDGLPA IGIQRGVQIA VPYRLYLPRR FYSQFSILAS VKPIDRTGGY
LFAIINAYDT VVDVGVLLEP SGEGHTNISL VYTNSRVDSS SKVVASFIVP HFVQQWTQFA
IKVTQTEVVL FFRCIRFASK TVSNLPSQLI MDDTHKLYVA SAGPIIQQGF EGAIQELKIH
DNPHDAEKQC DELWVSPVPP FICLRRFHSD YVTFSNSLGM SFNCMECSFL VETTQNGEDS
NERGCGVLVR CLECSSPFRS FLPIDIISTV FQPPIQDDEG SGSLPDAVKD ESLDGPRTVI
PIDPRKINFQ DVSSASQSHS QPGQKGETGP QGPVGPPGRD GDEGPRGPEG PMGPPGPPGP
AGPAGSGVYQ MEEGNGFGMM GPAGPMGPPG ERGPEGPEGP QGPHGRSFDR LTDEDIERIA
NYPGVKGEKG EPGVCEKSTD NYNSYSMAGE KGERGERGEK GERGETITVS PPAQTNSLVR
VLPTTVEVFA SGPLTDEGTL AFALSSQQLF LRVSNGWKEV MLGQYHPIVQ QQPSVPISSN
VDLSPDTHYK YWEAQTTEAA SSHSVILPPP RPLFGDQRSI PPPGPAHLTT SFKFGPNEKD
RVIHLIALNN PNNGNMRGLR GADLLCYRQA RQAGFVTTFR ALLASHAQDL VRIVHREDHT
SMVVNAKGER LFESWNKFMN GSPMDNVAIY TFDHTNMNTD DNWPDKWAWI GSDSRGMRDA
TGMCKDWRSE SGYDKGQAAS FGEGGRMISD LRNMRCDSKL AVLCVENISR YNIDRRPDPF
FMERDVITAF NAELASIYDS RPPISKNKIV EITKTALKAI KFYKHVVFSV EKFLGKCKAE
YKIPCLYVMD SILRQSKRQF KDKDVFCARF AKNFETTLVV LLQCSPTDRL KIARTINLWE
ANGVFSSEKI NEYRAICVAN GLEMDRDAVE KAVKGEKADL SIYERSGEKE KKERHHHHHH
RHREEHEGHT PAEPAVEMPS EEVPSGGVSE AALLNLIQNQ MFDIGQTVGR DLTLLRQVHS
MIVQNMKDKV EKERNANKQV SVKKLLSSGF DYSDEEDNEE EKEEPKAPPP PTQDELDRMA
ESLVMEKAAD IRRMHGDRIV KLQNAALEAK RAEQQRAAQD AAQAQQEKDA AVAQAQKMAA
QQQAAAAAAA AAASVASSQA QVQSSILGQP PPGPPFGLPP GMQLPPGFPG LPQVSMAGPG
GLSGLIQQNS LDNQMKALNS ILSNPLGILG QGPPPQINLQ HNPLFRMNPQ FAALAGGGDQ
AALQALLSQP PPSLPPMGIP PPGMNSGLSQ QQLQHLAGVG NGMGMGLGGS IGTSMNGPPS
GMGGMGMHPQ SMQPQGMPPQ GMSQMQKPPS LMDLDQDVLA QMMAQAPPSD EMDEQHSQME
RRESRESRDD DRDRRKKRDG ERDRDRDRDR GEKERDRGDR GDRRDRDRDR DRSEHRSKDH
KEKKRKRSRS RERRDRSRDR EDDKERRKMG LPSHPKDGTT TIASCTVWLG RLPQMNEEEL
RASIPELSPA NQVQLMHTRA CAYVTMKDRR SAVKLLDKAK GMRVRGKDIK ASWAAGNGTK
GDKWRSYWDE DRGISAIPHN ELPLDAMNDL CDGGWLDVST LPIHLRGIID EGGKVIDQTD
SATSLLDDTL SSHHSNSFLD LGQVQLPPTP DLSSIPNPMS HFNPNMNLGG PALMMPPMGG
QFMNLGLPNG LPPFVPSPMR GGMHGGRGGP GGHGGFMHSP MGGRGRGDWR GGSGRGGFMP
RGGGGRGGWN GGGPPSMDRI IGGGGSFGEP RRNTRWNTDD ATVSSTTMND DNDRPRMNDS
KDRHQTKIDN NSDDMEMELT HSRSINPIAV LHLFEDEKAL EISSSTRSIT SRQNFPENTF
RNIDTK
//
