ID A0A2B7XDI2_9EURO Unreviewed; 838 AA.
AC A0A2B7XDI2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 02-APR-2025, entry version 26.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS51873};
GN ORFNames=AJ79_06433 {ECO:0000313|EMBL:PGH06792.1};
OS Helicocarpus griseus UAMH5409.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Helicocarpus.
OX NCBI_TaxID=1447875 {ECO:0000313|EMBL:PGH06792.1, ECO:0000313|Proteomes:UP000223968};
RN [1] {ECO:0000313|EMBL:PGH06792.1, ECO:0000313|Proteomes:UP000223968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH5409 {ECO:0000313|EMBL:PGH06792.1,
RC ECO:0000313|Proteomes:UP000223968};
RA Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PGH06792.1}.
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DR EMBL; PDNB01000114; PGH06792.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B7XDI2; -.
DR STRING; 1447875.A0A2B7XDI2; -.
DR OrthoDB; 10009520at2759; -.
DR Proteomes; UP000223968; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR CDD; cd20353; Rcat_RBR_RNF216; 1.
DR CDD; cd16630; RING-HC_RBR_RNF216; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR051628; LUBAC_E3_Ligases.
DR InterPro; IPR047546; Rcat_RBR_RNF216.
DR InterPro; IPR047544; RING-HC_RBR_RNF216.
DR InterPro; IPR044066; TRIAD_supradom.
DR PANTHER; PTHR22770:SF42; FINGER PROTEIN (ZIN), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03910)-RELATED; 1.
DR PANTHER; PTHR22770; UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED; 1.
DR Pfam; PF01485; IBR; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51873; TRIAD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000223968};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT TRANSMEM 495..517
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 355..642
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT REGION 1..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..37
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..70
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..660
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..688
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 838 AA; 92823 MW; C1108B47B51049C9 CRC64;
MVLSLALPSF SSRPSSAQSK SSTSTSTSTS TSPSAKSGTA LSADGSSTPV TAFRRPSSAS
TPAQSSSSTA KEVAPAPPTS STITEALRGN PFGIVSRRKT SSDLVVTGNV EEEKERERVE
LNEALATLTQ LFPDVKVEVF RELLVRFDGK SRLHVCVEQL LRYKAEWVKG RWNVPEPDAK
GAGGAGNGGP EASRGAIAVD GNGDAQGRRT RWIPYEELFQ SEEYKAAVKS TLSQEFRGLS
RSAIDAVLAE VNFSYTRARP SLRELSRKSW RVTFGSLFPF KRKKEKDDHP LMVWQRMSDG
ELVPRLKESG CSELDRELYD AFLAPLLAQR KQNQEDKGLQ LAEELNKAEA EAMEALYECD
CCLSDVTFEQ ISTCSSHIIC FSCIRRTIHE ALFGQGWGKS IDHEKSTLRC IAPVAEGCEG
TLDPMIVKRA ILAEKAGAET YRKFEDRLAS ECLLKSQLKL IRCPFCSYAE IDPVYHPTAK
GITWRFRRGN LLPTIATTIF LLDLIPLLIL PVLYFLLFCP SMISTIFSAS LRNICLKTRT
QRFSCSNPSC GCDSCITCHK PWQDPHRCHE PLLLSLRTTV EAARTAAIKR TCPRCGVSFV
KSSGCNKLTC VCGYSMCYIC RKALGPPLRL AGGNNTPAAP RVRNRRPRRN IQNQNNIENE
PFGDANVNDM QADGYSDDDD NNGAVGDDDE PEGYKHFCEH FRVNPGSRCT ECNKCDLYLA
EDDEAVARRA GERAERQWRI RQGLLNPSSS SSSDSSGVND ALAKLNGISS GGQHHRAYRG
AAAAAAVGPL DFNYQFGGAD WKGRWRFWMR DVWRDGRWRG EGQWLIDRVV EMVIVVDT
//
