ID A0A2C5WTU9_9PEZI Unreviewed; 832 AA.
AC A0A2C5WTU9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 05-FEB-2025, entry version 24.
DE SubName: Full=Splicing factor U2AF-associated protein 2 {ECO:0000313|EMBL:PHH49447.1};
GN Name=uap2 {ECO:0000313|EMBL:PHH49447.1};
GN ORFNames=CFIMG_006950RA {ECO:0000313|EMBL:PHH49447.1};
OS Ceratocystis fimbriata CBS 114723.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Ceratocystidaceae; Ceratocystis.
OX NCBI_TaxID=1035309 {ECO:0000313|EMBL:PHH49447.1, ECO:0000313|Proteomes:UP000222788};
RN [1] {ECO:0000313|EMBL:PHH49447.1, ECO:0000313|Proteomes:UP000222788}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114723 {ECO:0000313|EMBL:PHH49447.1,
RC ECO:0000313|Proteomes:UP000222788};
RX PubMed=23931120; DOI=10.1016/j.funbio.2013.06.004;
RA Simpson M.C., Wilken P.M., Coetzee M.P., Wingfield M.J., Wingfield B.D.;
RT "Analysis of microsatellite markers in the genome of the plant pathogen
RT Ceratocystis fimbriata.";
RL Fungal Biol. 117:545-555(2013).
RN [2] {ECO:0000313|EMBL:PHH49447.1, ECO:0000313|Proteomes:UP000222788}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114723 {ECO:0000313|EMBL:PHH49447.1,
RC ECO:0000313|Proteomes:UP000222788};
RX PubMed=24563841; DOI=10.5598/imafungus.2013.04.02.14;
RA Wilken P.M., Steenkamp E.T., Wingfield M.J., de Beer Z.W., Wingfield B.D.;
RT "IMA Genome-F 1: Ceratocystis fimbriata: Draft nuclear genome sequence for
RT the plant pathogen, Ceratocystis fimbriata.";
RL IMA Fungus 4:357-358(2013).
CC -!- SIMILARITY: Belongs to the HTATSF1 family.
CC {ECO:0000256|ARBA:ARBA00007747}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHH49447.1}.
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DR EMBL; APWK03000203; PHH49447.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C5WTU9; -.
DR STRING; 1035309.A0A2C5WTU9; -.
DR OrthoDB; 10258585at2759; -.
DR Proteomes; UP000222788; Unassembled WGS sequence.
DR GO; GO:0005686; C:U2 snRNP; IEA:TreeGrafter.
DR GO; GO:0005684; C:U2-type spliceosomal complex; IEA:TreeGrafter.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd12281; RRM1_TatSF1_like; 1.
DR CDD; cd12285; RRM3_RBM39_like; 1.
DR FunFam; 3.30.70.330:FF:000105; HIV Tat-specific factor 1 homolog; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034393; TatSF1-like.
DR InterPro; IPR034392; TatSF1-like_RRM1.
DR PANTHER; PTHR15608:SF0; HIV TAT-SPECIFIC FACTOR 1; 1.
DR PANTHER; PTHR15608; SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS51917; PRU; 1.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Reference proteome {ECO:0000313|Proteomes:UP000222788};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 1..135
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 569..662
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 145..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 436..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..171
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..496
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..671
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 832 AA; 91951 MW; FB86E2495F3D97C4 CRC64;
MSTEPLIVFR AGRCDIDTTV TPPRVTPKPD PGYLYLYNGE DELIHLCWRK RSSSSNDQPD
LDLVMIPGDG NFLHYDSEAP SAKTNGRIYV LKFQSSSQRY LFWLQSAPEH PTIHSRLSER
DRKITDIVFN LLQGEEVDVD AELAALDEDD DEEEEEEEYE DEDEDEDEEM ADQTTTARGT
TGGAGADATG GDIRDEGEDA REGGADGGRA ATETTANVDS VVRNLLASLE GSRQLSDSPR
RPEPNDKPFP FLSHLLPTSV TVPIIDSGVS EEKIDQLINL LPPTLVVATA NSGTNSAEIS
QDPTTEMLES AKASLSLADK RDLVKRVLRS PQFAQSLGSL TMAIRDGGLP TIAEALQIDV
ENNGYMRGSA MPLGNATPSY VKMAAHVELN FPTDKSQFDS DDRISFSKLD QKYIAVHDDG
DEYEFDEAAQ HWVLCDEGDE GDEPPLPQNL DPSSKALLPS DMDSMSDTRK RKEAPTAADN
ELKSISNPSK VYSSTRSSRD GHRGFQRDTS YCARVGMRGY LPATCGFGNN TDSANVCSLP
NHQQDSNKQQ TKPRAQKKAK GPLPPRKNTA VYVTGIPNDA TLDEIHDLFS RKGGVVAEEI
DSGRPRIKMY TDVDGNFKGD ALIVFFKPQS VEMAIMLLDD TDFRFTSAGK PEGRIRVQEA
DSSYKKTKYE GNQDQQGGNK DAQAPTTRKN DQDRHKIIKK TQKLELKLAD WDDDQYPPDK
PVIKARWEKT VILSHMFTLK ELEEDPTALL DIKEDIRDEC SKLGTVTNVI LFDMEPEGIV
SVKFKEIEAA HACVRMMHGR NFGGQVVEAG LATGKEKFKQ SSKASLSDSD SD
//
