ID A0A2C9ULD0_MANES Unreviewed; 616 AA.
AC A0A2C9ULD0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 28-JAN-2026, entry version 24.
DE RecName: Full=NPH3 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MANES_14G134600v8 {ECO:0000313|EMBL:OAY31716.1};
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY31716.1, ECO:0000313|Proteomes:UP000091857};
RN [1] {ECO:0000313|Proteomes:UP000091857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RX PubMed=27088722; DOI=10.1038/nbt.3535;
RA Bredeson J.V., Lyons J.B., Prochnik S.E., Wu G.A., Ha C.M.,
RA Edsinger-Gonzales E., Grimwood J., Schmutz J., Rabbi I.Y., Egesi C.,
RA Nauluvula P., Lebot V., Ndunguru J., Mkamilo G., Bart R.S., Setter T.L.,
RA Gleadow R.M., Kulakow P., Ferguson M.E., Rounsley S., Rokhsar D.S.;
RT "Sequencing wild and cultivated cassava and related species reveals
RT extensive interspecific hybridization and genetic diversity.";
RL Nat. Biotechnol. 34:562-570(2016).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the NPH3 family. {ECO:0000256|PROSITE-
CC ProRule:PRU00982}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAY31716.1}.
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DR EMBL; CM004400; OAY31716.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9ULD0; -.
DR Gramene; Manes.14G134600.3.v8.1; Manes.14G134600.3.v8.1.CDS; Manes.14G134600.v8.1.
DR Gramene; Manes.14G134600.5.v8.1; Manes.14G134600.5.v8.1.CDS; Manes.14G134600.v8.1.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000091857; Chromosome 14.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd18312; BTB_POZ_NPY3-like; 1.
DR Gene3D; 3.30.710.10; Potassium Channel Kv1.1, Chain A; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR043454; NPH3/RPT2-like.
DR InterPro; IPR027356; NPH3_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR32370; OS12G0117600 PROTEIN; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF03000; NPH3; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS51649; NPH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000091857};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 9..79
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 194..492
FT /note="NPH3"
FT /evidence="ECO:0000259|PROSITE:PS51649"
FT COILED 532..566
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 616 AA; 68173 MW; 4F7538032E258904 CRC64;
MFCTTGLPSD IVVEVGDMSF HLHKFPLLSR SGVMERLIAE ASKEGEENCV INLHDSPGGA
KTFELVAKFC YGVKLELTSS NVVYLHCAAE HLEMTEDYGE GNLIMQTETF FNQVVLQNWK
DSLKALQTCD DSLPYAEELH ITKRCIESLA TKAYTDPNLL GWPTMEYGPM QSPGGSVLWN
GISTGARPKN SSSNWWYEDV STLSFPLYKR LISIMESRGI REEIIAGSLV FYAKKYLPGL
NRRQGASESS SRLLAVALAP PSEEDQKTFL EDIDRLLPMQ KGLVPTKFLF GLLRTALILK
ASPSCLSNLE KRIGMQLDQA TLEDLLMPSF SYSMETLYNV DCVQRILDHF LAMDQISGGA
SGGASGGASP SACSVDDGQL IGSPSLTPIT MVAKLIDGYL AEVAPDVNLK LSKFQALAAA
VPDYARPLDD GLYRAIDIYL KSHQWLAESD REQLCRLMDC QKLSLEACSH AAQNERLPLR
IIVQVLFFEQ LQLRTSIAGC FLVSDNLDGS RQLRSGIVGS TEGGWATAVR ENQVLKVGMD
NMRMRVSELE KECSNMRQEI EKMGRTKASS TWGNVSKKFG FKLKSQMCSA QEGAVSNQKN
NFNAKAKDRL GKLKKY
//
