ID A0A2G8LQX5_STIJA Unreviewed; 722 AA.
AC A0A2G8LQX5;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 02-APR-2025, entry version 28.
DE SubName: Full=Putative E3 ubiquitin-protein ligase RNF31 isoform 3 {ECO:0000313|EMBL:PIK62635.1};
GN ORFNames=BSL78_00427 {ECO:0000313|EMBL:PIK62635.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK62635.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK62635.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK62635.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK62635.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK62635.1}.
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DR EMBL; MRZV01000008; PIK62635.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8LQX5; -.
DR STRING; 307972.A0A2G8LQX5; -.
DR OrthoDB; 9978677at2759; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR GO; GO:0071797; C:LUBAC complex; IEA:InterPro.
DR GO; GO:0036435; F:K48-linked polyubiquitin modification-dependent protein binding; IEA:TreeGrafter.
DR GO; GO:0070530; F:K63-linked polyubiquitin modification-dependent protein binding; IEA:TreeGrafter.
DR GO; GO:1990450; F:linear polyubiquitin binding; IEA:TreeGrafter.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0097039; P:protein linear polyubiquitination; IEA:TreeGrafter.
DR CDD; cd20337; BRcat_RBR_HOIP; 1.
DR CDD; cd20351; Rcat_RBR_HOIP; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR InterPro; IPR047540; BRcat_RBR_RNF31-like.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR047542; Rcat_RBR_RNF31-like.
DR InterPro; IPR026254; RNF31-like.
DR InterPro; IPR041031; RNF31_C.
DR InterPro; IPR044066; TRIAD_supradom.
DR PANTHER; PTHR16004:SF2; E3 UBIQUITIN-PROTEIN LIGASE LUBEL; 1.
DR PANTHER; PTHR16004; RING FINGER PROTEIN 31-RELATED; 1.
DR Pfam; PF18091; E3_UbLigase_RBR; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR SMART; SM00647; IBR; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS51873; TRIAD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 341..578
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 100..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..151
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 722 AA; 82970 MW; E018235B6C2360B0 CRC64;
MDLFRRAAHQ EQNPVRGDHR APPRQIPGVK PRPAEQNAPQ VQHGPPVVVK RWRCEHCTYL
NEASDGNICT MCSRTTTSPQ MEEHVTEYPV TIIRAEEVMT QSGPPHGLER PLPRTMNALE
KRPEHEQPRY ETKEEENARR TREEEQRKRD EEEVESQQKQ ENLTLRLLIM YRNQGNFNAN
KEERYSLEEV ATAWAVLERE GIMNMQPVEW LDKHLKKQLE LFGGDVLREF CRRYNLNPKD
YHQWIPNEYV HPAWLKNDGV REKTAAECLA LLQEKVKDIC AENPDVDYEE HAAKLLLEGG
FDSENLSWGL QLSAAEEKQD EIDGWLGKMW DVAYSVEGAI EKIENSMLNE ADKKELIGIP
SCQCHICTEC FTQNFTLLAQ NTPCVYKFAC PSCNEPKLEE ISEDEFHRYF TYLGMVLKQH
LNPADFELYQ QKLVTWGLIK DENFRWCANG CSNGFINERD DVKIQCTNCK KFQCFDCQKP
WQEQHEGISC EEFEQWKKDN DPEFQAQGLA AHLKENGINC PNCKMRYELA KGGCMHFKCA
QCMHEFCCGC NLPFLKYPNC RKFPSCQGKG LHAHHPRDCL YHLRDQECET LQKLLQDNGV
EYNRANAAAN LPEEDGCPVK EQREDPDGLV DVNCGKELIA AAGLCLTHYK EYLVSLINQS
KIDPADILTA GELGAALKRD GQNVPVIQAG EANEAYQERL RQLLKAQIPL HEGGEAVAAN
RL
//
