ID A0A2I2Z8B0_GORGO Unreviewed; 147 AA.
AC A0A2I2Z8B0;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 10-JUN-2026, entry version 29.
DE RecName: Full=Probable ribosome biogenesis protein RLP24 {ECO:0000256|ARBA:ARBA00039784};
DE AltName: Full=Ribosomal L24 domain-containing protein 1 {ECO:0000256|ARBA:ARBA00042993};
DE AltName: Full=Ribosomal protein L24-like {ECO:0000256|ARBA:ARBA00082129};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000043336.1, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000043336.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000043336.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JAN-2026) to UniProtKB.
CC -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit.
CC Ensures the docking of GTPBP4/NOG1 to pre-60S particles.
CC {ECO:0000256|ARBA:ARBA00037035}.
CC -!- SUBUNIT: Associated with nucleolar and cytoplasmic pre-60S particles.
CC At the end of biogenesis it dissociates from cytoplasmic pre-60S
CC particles and is likely to be exchanged for its ribosomal homolog,
CC RPL24. {ECO:0000256|ARBA:ARBA00047058}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL24 family.
CC {ECO:0000256|ARBA:ARBA00005647}.
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DR EMBL; CABD030043945; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I2Z8B0; -.
DR STRING; 9593.ENSGGOP00000043336; -.
DR Ensembl; ENSGGOT00000058966.1; ENSGGOP00000043336.1; ENSGGOG00000041514.1.
DR GeneTree; ENSGT00950000183105; -.
DR InParanoid; A0A2I2Z8B0; -.
DR OMA; RKARWIK; -.
DR Proteomes; UP000001519; Chromosome 6.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR CDD; cd00472; Ribosomal_L24e_L24; 1.
DR FunFam; 2.30.170.20:FF:000001; probable ribosome biogenesis protein RLP24; 1.
DR Gene3D; 2.30.170.20; Ribosomal protein L24e; 1.
DR InterPro; IPR038630; L24e/L24_sf.
DR InterPro; IPR056366; Ribosomal_eL24.
DR InterPro; IPR000988; Ribosomal_eL24-rel_N.
DR PANTHER; PTHR10792; 60S RIBOSOMAL PROTEIN L24; 1.
DR PANTHER; PTHR10792:SF30; TRASH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01246; Ribosomal_L24e; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT DOMAIN 4..58
FT /note="Large ribosomal subunit protein eL24-related N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF01246"
SQ SEQUENCE 147 AA; 17609 MW; 52E55AAE5AD19D1D CRC64;
MRQRPLYPGH GMMFVHNNCK LFRFCKSKCH KNFKKKCSPR KARWIKAFQN AAGKELTVDN
SFEFEKRRNE PIKYQRELWN KTIDAMKQIE EIKQKCQAKF IMNRLNKNKE LQKVQGIKEV
KLAGKEKQLE EKMVQQLQED VDMKDAS
//
