ID A0A2K1Q366_9GAMM Unreviewed; 643 AA.
AC A0A2K1Q366;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 28-JAN-2026, entry version 26.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=Lysil_1118 {ECO:0000313|EMBL:PNS09489.1};
OS Solilutibacter silvestris.
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC Lysobacterales; Lysobacteraceae; Solilutibacter.
OX NCBI_TaxID=1645665 {ECO:0000313|EMBL:PNS09489.1, ECO:0000313|Proteomes:UP000236220};
RN [1] {ECO:0000313|EMBL:PNS09489.1, ECO:0000313|Proteomes:UP000236220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM20-91 {ECO:0000313|EMBL:PNS09489.1,
RC ECO:0000313|Proteomes:UP000236220};
RA Zhang D.-C., Albuquerque L., Franca L., Froufe H.J.C., Barroso C., Egas C.,
RA Da Costa M., Margesin R.;
RT "Lysobacter sylvestris genome.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNS09489.1}.
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DR EMBL; NPZB01000001; PNS09489.1; -; Genomic_DNA.
DR RefSeq; WP_103074535.1; NZ_NPZB01000001.1.
DR AlphaFoldDB; A0A2K1Q366; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000236220; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR048931; WHD_2nd_SelB_bact.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF21214; WHD_2nd_SelB_bact; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:PNS09489.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000236220}.
FT DOMAIN 1..177
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 643 AA; 69931 MW; AAEDD5123340CF2A CRC64;
MIVGTAGHID HGKTSLVRAL TGIDTDRLKE EKARGISIEL GYAYVPIEAD TAEDSATILG
FVDVPGHERF VHTMVAGATG IDFALLVIAA DDGVMPQTRE HLAILELLGV RHGAIALTKV
DRVDQQRVAD VEAEIATLLA KSPLRESLLF ACNSTSTDDP GITALRDHLH AVAASPRHDA
GNDLRDELFR MPVDRVFTLP GHGTMVTGAI HGGQIETSAT PRLMPAGTTV RVRSIHAQNR
ASARAVAGQR CALNLAAIAC EDIARGDWIA DPRAFVATTR VDVRLRLSVD APPLRNWTPL
HIHWGTMDRL AHAVVLDDGD GERGALVQLV FAAPVCAMCG DRFIARDSGA NTTIGGGIVL
DPNPPQRRRR SPARLAWLSA LEQLAAGDGI APLLQEAPTG VAMSALVRYC RRPAERIALP
EDMLRIATRD DTFIILATHW QALRAKVVVA VSEWHVRHPD EPGIDSGRLQ RSTLPNLAPG
LWQALLHDLQ ANGTLQRLGA WWCLPGHDSA PPEHERALLQ RLVPLLHAGG FDPPWVRTLA
TQTGEDEEKT RGILRRAAAR GELFQVVPDL FYDPRRIAEL AATLAALVQD GGATDAAAFR
DAIGLGRKRS IQILEFFNRV GYTRRVGDTH RPRDDMRWNA NQT
//
