ID A0A2K5D1Q6_AOTNA Unreviewed; 751 AA.
AC A0A2K5D1Q6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 28-JAN-2026, entry version 36.
DE SubName: Full=MYB proto-onco like 1 {ECO:0000313|Ensembl:ENSANAP00000014861.1};
GN Name=MYBL1 {ECO:0000313|Ensembl:ENSANAP00000014861.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000014861.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000014861.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSANAP00000014861.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A2K5D1Q6; -.
DR Ensembl; ENSANAT00000032695.1; ENSANAP00000014861.1; ENSANAG00000025284.1.
DR GeneTree; ENSGT00940000157709; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:UniProtKB-ARBA.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:TreeGrafter.
DR CDD; cd00167; SANT; 3.
DR FunFam; 1.10.10.60:FF:000010; Transcriptional activator Myb isoform A; 1.
DR FunFam; 1.10.10.60:FF:000016; Transcriptional activator Myb isoform A; 1.
DR FunFam; 1.10.10.60:FF:000042; Transcriptional activator Myb isoform A; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 3.
DR InterPro; IPR015395; C-myb_C.
DR InterPro; IPR009057; Homeodomain-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR050560; MYB_TF.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR012642; Tscrpt_reg_Wos2-domain.
DR PANTHER; PTHR45614; MYB PROTEIN-RELATED; 1.
DR PANTHER; PTHR45614:SF9; MYB-RELATED PROTEIN A; 1.
DR Pfam; PF09316; Cmyb_C; 1.
DR Pfam; PF07988; LMSTEN; 1.
DR Pfam; PF13921; Myb_DNA-bind_6; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00717; SANT; 3.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51294; HTH_MYB; 3.
DR PROSITE; PS50090; MYB_LIKE; 3.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 34..81
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 34..81
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 82..137
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 82..133
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 134..184
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 138..188
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 426..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 751 AA; 85523 MW; 96D213798EDE4CEE CRC64;
WARTSRDPDE DDDLQYADHD YEVPQQKGLK KLWNRVKWTR DEDDKLKKLV EQHGTDDWTL
IASRLQNRSD FQCQHRWQKV LNPELIKGPW TKEEDQRVIE LVQKYGPKKW SLIAKHLKGR
IGKQCRERWH NHLNPEVKKS SWTEEEDRII YEAHKRLGNR WAEIAKLLPG RTDNSIKNHW
NSTMRRKVEQ EGYLQDGIKS EQSSSKLQYK PYAAMDHLQT QNQFYIPVQI PGYQYVSPEG
NCIEHVQTTS AFIQQPFIDE DPDKEKKIKE LELLLMSAEN EVKRKRIPSQ TGSCSGWSGS
FLMDDNMSNT LNSLDEHTSE FYSMGENQPV SAQQNSPTKF LAVEANAVLS SLQTIPEFAE
TLELIESDPV AWSDVTSFDI SADAAASPIK STPVKLMRIQ HNEGAVECQF NVSVVLEGKK
NICNGGSSEP VPSPNMAKFS TPPAILRKKR RMRAGHSPGS ELRDGSLNDG GNAALKHTPL
KTLPFSPSQF FNTCPGNEQL NIENPSFTST PICGQKVLIT TPLHKETTPK EQKENVGFRT
PTIRRSILGT TPRTPTPFKN ALAAQEKKYG PLKIVSQPLA FLEEDIREVL KEETGTDIFL
KEEDEPAYKS CKQENTASGK KVRKSLVLDN WEKEESGTQL LTEDISDMQS ENIFTTSLLM
IPLLEIHDNR CNLTPEKQDI NSTNKTYTLT IKKPNPNTSQ VVKLEKNLQS NCEWETVVYG
KTEDQLIMTE QARRYLSTYT ATSSTSRALI L
//
