ID A0A2L0PJC4_VITS1 Unreviewed; 593 AA.
AC A0A2L0PJC4;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 07-OCT-2020, sequence version 2.
DT 18-JUN-2025, entry version 28.
DE SubName: Full=GDSL-like lipase/acylhydrolase {ECO:0000313|EMBL:AUZ04283.2};
GN ORFNames=ADP71_04990 {ECO:0000313|EMBL:AUZ04283.2};
OS Vitreoscilla sp. (strain C1).
OC Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC Neisseriaceae; Vitreoscilla.
OX NCBI_TaxID=96942 {ECO:0000313|EMBL:AUZ04283.2, ECO:0000313|Proteomes:UP000238938};
RN [1] {ECO:0000313|Proteomes:UP000238938}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C1 {ECO:0000313|Proteomes:UP000238938};
RA Veseli I.A., Stark B.C., Pombert J.-F., Juarez O.;
RT "Genetic Analysis of ATP Synthesis in Vitreoscilla sp. C1.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000256|ARBA:ARBA00008668}.
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DR EMBL; CP019644; AUZ04283.2; -; Genomic_DNA.
DR RefSeq; WP_019957281.1; NZ_CP019644.2.
DR AlphaFoldDB; A0A2L0PJC4; -.
DR KEGG; vit:ADP71_04990; -.
DR Proteomes; UP000238938; Chromosome.
DR GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR CDD; cd01847; Triacylglycerol_lipase_like; 1.
DR Gene3D; 2.40.128.130; Autotransporter beta-domain; 1.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR005546; Autotransporte_beta.
DR InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR050592; GDSL_lipolytic_enzyme.
DR InterPro; IPR017186; Lipase_autotranspt_EstA.
DR InterPro; IPR006315; OM_autotransptr_brl_dom.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR NCBIfam; TIGR01414; autotrans_barl; 1.
DR PANTHER; PTHR45642; GDSL ESTERASE/LIPASE EXL3; 1.
DR PANTHER; PTHR45642:SF141; SECRETED EFFECTOR PROTEIN SSEJ; 1.
DR Pfam; PF03797; Autotransporter; 1.
DR Pfam; PF00657; Lipase_GDSL; 1.
DR PIRSF; PIRSF037375; Autotrns_EstA; 1.
DR SMART; SM00869; Autotransporter; 1.
DR SUPFAM; SSF103515; Autotransporter; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
DR PROSITE; PS51208; AUTOTRANSPORTER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:AUZ04283.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000238938};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..593
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5026724048"
FT DOMAIN 319..593
FT /note="Autotransporter"
FT /evidence="ECO:0000259|PROSITE:PS51208"
FT ACT_SITE 33
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR037375-1"
FT ACT_SITE 265
FT /evidence="ECO:0000256|PIRSR:PIRSR037375-1"
FT ACT_SITE 268
FT /evidence="ECO:0000256|PIRSR:PIRSR037375-1"
SQ SEQUENCE 593 AA; 62965 MW; 494135D700369091 CRC64;
MKTTYLAACV ACLGLSVLVQ AQPFSNTYFM GDSLTDSGQF MGQRFTTNPG QVWSQHLAAH
LGGNANPSRL GGNNYAVGGA RVGEDTSDTV AGVTVAIPSI KTQIAQLKAS QGGKLDSRAL
YAVWGGANDL FAITAGAPAQ ATMTAAIIDH TTAIHSLSSA GATYILVPNL PNLGMTPAFR
GNEAAGTQLS QTYNQALYEP FIKNSVKTNI IPLDIYSLLD DVSKNPASYG FKNVTTPACG
TTSSVQCGPA QLLEPNADQT YLFADGVHPT SKAHEVVGQY AAAVLQAPAQ MAVLGRAANQ
AGLAQMQHVD RRLHNIAPLQ DGKTAVWVQG GVALGSGNAA NSELDGAGGK VVIGVDKRLG
EWTVGTYVAH DSIDGKTGHI HQYDQQRLAG GVYGRWQSGS AWVNAQAYYA NLDVDTQRQL
ALGNKTQNHQ ASGDGDQYGV RLMTGLNWQH GDLSHGPVVG VSMQKASIDR LQESGADFSA
MTFDALKQES VQSSLGYQMA YQINPKWDTF ASLQWQREFK DGVDKVGAHL NSMDALHFEV
PVNEDKARNS GLLELGVNGK INEQWHLGAG VNAQFGDAVN AQTAVYLNTS YRF
//
