ID   A0A2N3PIA9_9HELI        Unreviewed;       422 AA.
AC   A0A2N3PIA9;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   28-JAN-2026, entry version 19.
DE   SubName: Full=Apolipoprotein N-acyltransferase {ECO:0000313|EMBL:PKT80399.1};
GN   ORFNames=BCM31_03165 {ECO:0000313|EMBL:PKT80399.1};
OS   Helicobacter winghamensis.
OC   Bacteria; Pseudomonadati; Campylobacterota; Epsilonproteobacteria;
OC   Campylobacterales; Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=157268 {ECO:0000313|EMBL:PKT80399.1, ECO:0000313|Proteomes:UP000233350};
RN   [1] {ECO:0000313|EMBL:PKT80399.1, ECO:0000313|Proteomes:UP000233350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=295_13 {ECO:0000313|EMBL:PKT80399.1,
RC   ECO:0000313|Proteomes:UP000233350};
RA   Zanoni R.G., Florio D., Caffara M., Renzi M., Parisi A., Pasquali F.,
RA   Manfreda G.;
RT   "Detection of Helicobacter winghamensis from caecal content of red fox
RT   (Vulpes vulpes).";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC   -!- SIMILARITY: Belongs to the CN hydrolase family. Apolipoprotein N-
CC       acyltransferase subfamily. {ECO:0000256|ARBA:ARBA00010065}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKT80399.1}.
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DR   EMBL; MBPK01000043; PKT80399.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N3PIA9; -.
DR   STRING; 556267.HWAG_00884; -.
DR   OrthoDB; 9804277at2; -.
DR   Proteomes; UP000233350; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016410; F:N-acyltransferase activity; IEA:InterPro.
DR   GO; GO:0042158; P:lipoprotein biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1.
DR   InterPro; IPR004563; Apolipo_AcylTrfase.
DR   InterPro; IPR003010; C-N_Hydrolase.
DR   InterPro; IPR036526; C-N_Hydrolase_sf.
DR   InterPro; IPR059109; Lnt_membrane_dom.
DR   NCBIfam; TIGR00546; lnt; 1.
DR   PANTHER; PTHR38686; APOLIPOPROTEIN N-ACYLTRANSFERASE; 1.
DR   PANTHER; PTHR38686:SF1; APOLIPOPROTEIN N-ACYLTRANSFERASE; 1.
DR   Pfam; PF26365; ApoNAT_membrane; 1.
DR   SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1.
DR   PROSITE; PS50263; CN_HYDROLASE; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW   ECO:0000313|EMBL:PKT80399.1};
KW   Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Lipoprotein {ECO:0000313|EMBL:PKT80399.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233350};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PKT80399.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        39..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        60..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        89..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        118..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        151..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          206..422
FT                   /note="CN hydrolase"
FT                   /evidence="ECO:0000259|PROSITE:PS50263"
SQ   SEQUENCE   422 AA;  48827 MW;  F2E53F3E06EF4D71 CRC64;
     MLGQKVLANR LHGILAGILC ALFLSAFIYL EHFLDNKNFP LYSTLFAILG LFLYFKLSRL
     GAFVCGGILG ILWFYWVGFS FRFYDLSHLI PLVWIVFFVV YGALFYLFCF FSSPFYRLVA
     LTLSSFIHPF GFNWFIPEVI LTKSYFFPSK FTLFLLLCSI LILSAFLAKK LYKTSLIWLC
     SFALLLPHNT EIKKDSNIMP LRIKTTHFEV PQDERWQTNQ MPNILTQNFE TILKAKNAGY
     DLVILPETAF PLSLNLQSAL LEKLKEESKE IAILTGAIFQ DSIQEKPRFF NSAYLFQNGE
     MQVFHKLILV PFGEKIPLPN FIAKWMNAFF FDGAQDFIAQ DFIAPNFAWI KNQKFQIAIC
     YEATRDEFYA NSPSNLIAIS NNAWFVPSIE PTLQKLLMLY FSKNHNTTIY HSSNASEDFT
     LH
//