ID A0A2N5HEB0_9BACI Unreviewed; 258 AA.
AC A0A2N5HEB0;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 02-APR-2025, entry version 16.
DE RecName: Full=Sulfur carrier protein FdhD {ECO:0000256|HAMAP-Rule:MF_00187};
GN Name=fdhD {ECO:0000256|HAMAP-Rule:MF_00187};
GN ORFNames=CVD27_13050 {ECO:0000313|EMBL:PLS03869.1};
OS Neobacillus cucumis.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Neobacillus.
OX NCBI_TaxID=1740721 {ECO:0000313|EMBL:PLS03869.1, ECO:0000313|Proteomes:UP000234950};
RN [1] {ECO:0000313|EMBL:PLS03869.1, ECO:0000313|Proteomes:UP000234950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V32-6 {ECO:0000313|EMBL:PLS03869.1,
RC ECO:0000313|Proteomes:UP000234950};
RA Seuylemezian A., Cooper K., Vaishampayan P.;
RT "Comparitive Functional Genomics of Dry Heat Resistant strains isolated
RT from the Viking Spacecraft.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC sulfur carrier protein that transfers sulfur from IscS to the
CC molybdenum cofactor prior to its insertion into FDH.
CC {ECO:0000256|HAMAP-Rule:MF_00187}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00187}.
CC -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000256|HAMAP-
CC Rule:MF_00187}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_00187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLS03869.1}.
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DR EMBL; PGVE01000050; PLS03869.1; -; Genomic_DNA.
DR RefSeq; WP_101648345.1; NZ_PGVE01000050.1.
DR AlphaFoldDB; A0A2N5HEB0; -.
DR OrthoDB; 9782042at2; -.
DR Proteomes; UP000234950; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.20.10; -; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR HAMAP; MF_00187; FdhD; 1.
DR InterPro; IPR016193; Cytidine_deaminase-like.
DR InterPro; IPR003786; FdhD.
DR NCBIfam; TIGR00129; fdhD_narQ; 1.
DR PANTHER; PTHR30592; FORMATE DEHYDROGENASE; 1.
DR PANTHER; PTHR30592:SF1; SULFUR CARRIER PROTEIN FDHD; 1.
DR Pfam; PF02634; FdhD-NarQ; 1.
DR PIRSF; PIRSF015626; FdhD; 1.
DR SUPFAM; SSF53927; Cytidine deaminase-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00187};
KW Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150,
KW ECO:0000256|HAMAP-Rule:MF_00187};
KW Reference proteome {ECO:0000313|Proteomes:UP000234950}.
FT ACT_SITE 87
FT /note="Cysteine persulfide intermediate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00187"
SQ SEQUENCE 258 AA; 28862 MW; 901CFDDC514A25F4 CRC64;
MSRKGCPDEY PITLIINGYE IAVFQLTKYD LIDWAYGYLF SEGFIQDASD IEAIHIDEEM
GAIHVSLHSH FDEEQVFSKK KHYTAGCGRG VTFFSMTDVK NFAKVSSNKK YELSYLLKKR
SEFAQNSSLY LETGGMHGAC MVEEDGMMTI REDIGRHNAV DKIIGCALRK GLSPERLILL
TTGRVSYEML SKAAKFGFPV IGSRTAATKQ AVQLAKFLNL EVIGYLRGKM ATIYTSAGRV
NNDLTQEIDF ERSIEGGN
//
