ID A0A2P4S8S4_BAMTH Unreviewed; 393 AA.
AC A0A2P4S8S4;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 02-APR-2025, entry version 24.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=CIB84_015729 {ECO:0000313|EMBL:POI20524.1};
OS Bambusicola thoracicus (Chinese bamboo-partridge) (Perdix thoracica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Perdicinae; Bambusicola.
OX NCBI_TaxID=9083 {ECO:0000313|EMBL:POI20524.1, ECO:0000313|Proteomes:UP000237246};
RN [1] {ECO:0000313|EMBL:POI20524.1, ECO:0000313|Proteomes:UP000237246}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RTK389 {ECO:0000313|EMBL:POI20524.1};
RC TISSUE=Blood {ECO:0000313|EMBL:POI20524.1};
RA Tiley G.P., Kimball R.T., Braun E.L., Burleigh J.G.;
RT "Comparison of the Chinese Bamboo Partridge and Red Junglefowl genome
RT sequences highlights the importance of demography in genome evolution.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POI20524.1}.
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DR EMBL; PPHD01082326; POI20524.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P4S8S4; -.
DR OrthoDB; 1431934at2759; -.
DR Proteomes; UP000237246; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20338; BRcat_RBR_RNF19; 1.
DR CDD; cd20355; Rcat_RBR_RNF19; 1.
DR FunFam; 1.20.120.1750:FF:000017; RBR-type E3 ubiquitin transferase; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 1.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51873; TRIAD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000237246};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT TRANSMEM 161..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..151
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT REGION 290..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 358..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..314
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 393 AA; 42039 MW; DD16A775FA0D12AC CRC64;
MHSLAAVLGC GGRPWPPLAP ANYLLFPHSY AVIAYGFAEC PRLTCGREGC GTEFCYHCRQ
LWHPDGPCAA APLASSLASP STQLVYTEES ANVEAEDIKV CPRCSAFIMK INDGSCNRMN
CTVCGCLFCW LCLQEISDVH FLSPSGCTFW GKRPWSRTQK ILWQLGMVLG APMVISLVAG
IAVPVIIIGL PIYTGRKVLG QSRRSSLSPC QQCFSVTSGV LLSLFVSPII TAVTVGIGVP
LMLTYVYGVV VLSLCRSRSS CGRSQPGDLG VVELENLTKL NELWSVLPSP KGAEDGVPDT
ATSFPSSSHS PRPRVMWKEQ DSHSASTMVL AGSTLSDTSY REGINIEVEV AIESVPHPTR
EQSLCSPQSG QSLSGDSLEG TSDRCSVTGA PAE
//
