ID A0A2P5IAJ3_9PEZI Unreviewed; 714 AA.
AC A0A2P5IAJ3;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 02-APR-2025, entry version 24.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=DHEL01_v202081 {ECO:0000313|EMBL:POS79521.1};
OS Diaporthe helianthi.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Diaporthales; Diaporthaceae; Diaporthe.
OX NCBI_TaxID=158607 {ECO:0000313|EMBL:POS79521.1, ECO:0000313|Proteomes:UP000094444};
RN [1] {ECO:0000313|EMBL:POS79521.1, ECO:0000313|Proteomes:UP000094444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7/96 {ECO:0000313|EMBL:POS79521.1,
RC ECO:0000313|Proteomes:UP000094444};
RA Baroncelli R.;
RT "Polyketide synthases of a Diaporthe helianthi virulent isolate.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POS79521.1}.
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DR EMBL; MAVT02000107; POS79521.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P5IAJ3; -.
DR STRING; 158607.A0A2P5IAJ3; -.
DR InParanoid; A0A2P5IAJ3; -.
DR OrthoDB; 9977870at2759; -.
DR Proteomes; UP000094444; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20335; BRcat_RBR; 1.
DR CDD; cd22584; Rcat_RBR_unk; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000094444};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 201..403
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 205..250
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 58..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 400..460
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 595..640
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 714 AA; 81255 MW; 528205B62F77ADFE CRC64;
MGSLATQLPT AQNASPADPV ITQAPHELDD LSYLVEVLRS VETEQHIEQD LINRAAELGI
SLPPPPSSPS EDLSCPGPES DAALSSTHAR NTSSGSDNTA DTAMTSNPPS RPGTGAGQRE
NPPPLPSSRA RSRSLNFSTY DKYLAQLEPN LCQPKILKRP PTPTDNTPSL FSVSTRKSYI
SIKNGLKAKV RWKRQSHTPS TTLSCICCRD DFNKQNDLQT LPCGHTYCGN CLRIMIEQST
TDESKMPPRC CTQPIPSTTI RNLLNRDEQQ LFLKAVQQYS TPWEARIFCP NPCCNEFIPP
RSRIDPKHPF DVVCRECRTR VCIWCKRDAH PVGQDCPNDH ELDQVLRMGE KSGWRRCYKC
RTLVELTQGC THMTCRCKAQ FCYICGAVWD PAVGCPNFCN GEEELERRRM EEAAREAELE
AEKAAREAAA AAAERERHQA EKRTQACEEF KRLKEEQEDE KWRFRTFERK TKWVMWTRHE
ERKHKLNEKY SDQIDKMKER HAKTEQHLEE RQIAAEIELR ASLEQAEKSV RIRVKHMEAY
CKALGRSSMS GAGSDMPPRV ITERHLRELG QQHNALEGMA RLHQAKINVL RDRQAKRMEE
LLERQESELQ KQREKRDQEM EDLVAELANE EDALAKVFKD RKGRLVRRWE LAIEILRVTK
EKETGVKFAP MPVPAWAAEA PSCVDGPGPE DDGLAVVHEE EEKRGDTEAT AIKS
//
