ID   A0A2T4BNQ0_9HYPO        Unreviewed;       835 AA.
AC   A0A2T4BNQ0;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   02-APR-2025, entry version 20.
DE   RecName: Full=Mitochondrial escape protein 2 {ECO:0000256|ARBA:ARBA00020222, ECO:0000256|RuleBase:RU367108};
GN   ORFNames=BBK36DRAFT_1165434 {ECO:0000313|EMBL:PTB70948.1};
OS   Trichoderma citrinoviride.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX   NCBI_TaxID=58853 {ECO:0000313|EMBL:PTB70948.1, ECO:0000313|Proteomes:UP000241546};
RN   [1] {ECO:0000313|Proteomes:UP000241546}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TUCIM 6016 {ECO:0000313|Proteomes:UP000241546};
RG   DOE Joint Genome Institute;
RA   Atanasova L., Chenthamara K., Zhang J., Grujic M., Henrissat B., Kuo A.,
RA   Aerts A., Salamov A., Lipzen A., Labutti K., Barry K., Miao Y.,
RA   Rahimi M.J., Shen Q., Grigoriev I.V., Kubicek C.P., Druzhinina I.S.;
RT   "Multiple horizontal gene transfer events from other fungi enriched the
RT   ability of initially mycotrophic Trichoderma (Ascomycota) to feed on dead
RT   plant biomass.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in maintaining the mitochondrial genome and in
CC       controlling the mtDNA escape. Involved in the regulation of mtDNA
CC       nucleotide structure and number. May have a dispensable role in early
CC       maturation of pre-rRNA. {ECO:0000256|ARBA:ARBA00025276,
CC       ECO:0000256|RuleBase:RU367108}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000256|ARBA:ARBA00004434, ECO:0000256|RuleBase:RU367108}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004434,
CC       ECO:0000256|RuleBase:RU367108}.
CC   -!- SIMILARITY: Belongs to the YME2 family. {ECO:0000256|ARBA:ARBA00010320,
CC       ECO:0000256|RuleBase:RU367108}.
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DR   EMBL; KZ680207; PTB70948.1; -; Genomic_DNA.
DR   RefSeq; XP_024754268.1; XM_024894775.1.
DR   AlphaFoldDB; A0A2T4BNQ0; -.
DR   GeneID; 36602893; -.
DR   OrthoDB; 10267654at2759; -.
DR   Proteomes; UP000241546; Unassembled WGS sequence.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IEA:UniProtKB-UniRule.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-UniRule.
DR   CDD; cd12433; RRM_Yme2p_like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR018850; Mt_escape_2_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR039627; Yme2_C.
DR   InterPro; IPR034260; Yme2_RRM.
DR   PANTHER; PTHR32198; MITOCHONDRIAL ESCAPE PROTEIN 2; 1.
DR   PANTHER; PTHR32198:SF2; MITOCHONDRIAL ESCAPE PROTEIN 2; 1.
DR   Pfam; PF10443; RNA12; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR   PROSITE; PS50102; RRM; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367108};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW   ECO:0000256|RuleBase:RU367108};
KW   Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792,
KW   ECO:0000256|RuleBase:RU367108};
KW   mRNA processing {ECO:0000256|RuleBase:RU367108};
KW   Reference proteome {ECO:0000313|Proteomes:UP000241546};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176,
KW   ECO:0000256|RuleBase:RU367108};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU367108};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU367108}.
FT   TRANSMEM        288..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367108"
FT   DOMAIN          180..272
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   REGION          20..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   835 AA;  93248 MW;  AD7A55961E892E6F CRC64;
     MRYRAGQRIW ETTSAIPLSD GNLTGKKQEL SPSEEQESGR FDVKPNESIL FFDNLFPLKL
     TPVLSLLSRR TETDQQLTDL LQRFNSSSLG IMDPIQLVKR AIPDNLPIKV TEIMPRLKDG
     GAFVKFEYDP SLSASEIEAK LLKKLREEPV KPWFNPFGRI RARLVRGVPW LEDLHRYPST
     LVMVEFVPPE PGAAAAELPE EVLYSLFRKY GKIADIIPQP ADSKITPRYA QIGFPVLRDA
     IMARNCLHGF VLGEAQGGGK NGTKLRLSYV KKEKGHSIWN WITSHPRIVI PIVAALIAGV
     SVMIFDPIRL FFIKVHVQHS LRYTDWRIYK WFKSQTGSFS FHKKQEHIEG LGTIWKHRKD
     LIEQLQSWLD GSSDTFIVVT GPRGSGKAEM VMSQALSGRK NVLLIDCKPI TEANGEAGTI
     KRLATAVGYR PVFSWANSIS SMVDLAVQGT TGVKSGFSET LESQLNKILH TTATALKTVA
     LSERSKADKD INLSEDAYLE AHPERRPVIV VDNFLHKSED SSLVYDMIAD WAATIVQNNV
     AHVVFLTSDS AYSKSLTKAM PDRVFRTLSL GDLDADVAKN FVITRLEEDW KREAQEEAEQ
     SDEEKKAIPR PNLAGLDEGI KVLGGRLTDL EFLARRLRAG QTPREAVEEI VTEDATDIVK
     MYLLGRTADA DRKWSTEQAW HLIKSLSENP TLRYHQVLLS PTFASSLSSN ATNGEAAIES
     LAGSELITVT THQGRPQTIT AGKPLHQAAF GVLVKDRVLR AKMDLAVLNE MAKVEAKNID
     AVEKELQLLG GLPRHTGESA GRVMYLLGKL DAGQRKIAQL EREMGGLKRI MNEEY
//