ID A0A2U3V5M4_TURTR Unreviewed; 156 AA.
AC A0A2U3V5M4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 28-JAN-2026, entry version 34.
DE RecName: Full=Protein SYS1 homolog {ECO:0000256|ARBA:ARBA00014516, ECO:0000256|PIRNR:PIRNR031402};
GN Name=SYS1 {ECO:0000313|RefSeq:XP_004322093.1,
GN ECO:0000313|RefSeq:XP_019799438.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_004322093.1};
RN [1] {ECO:0000313|RefSeq:XP_004322093.1, ECO:0000313|RefSeq:XP_019799438.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_004322093.1,
RC ECO:0000313|RefSeq:XP_019799438.1};
RG RefSeq;
RL Submitted (APR-2025) to UniProtKB.
CC -!- FUNCTION: Involved in protein trafficking. May serve as a receptor for
CC ARFRP1. {ECO:0000256|ARBA:ARBA00025508}.
CC -!- SUBUNIT: Interacts with ARFRP1. {ECO:0000256|ARBA:ARBA00011215}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653, ECO:0000256|PIRNR:PIRNR031402}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004653,
CC ECO:0000256|PIRNR:PIRNR031402}.
CC -!- SIMILARITY: Belongs to the SYS1 family. {ECO:0000256|ARBA:ARBA00008160,
CC ECO:0000256|PIRNR:PIRNR031402}.
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DR RefSeq; XP_004322093.1; XM_004322045.3.
DR RefSeq; XP_019799438.1; XM_019943879.2.
DR AlphaFoldDB; A0A2U3V5M4; -.
DR STRING; 9739.ENSTTRP00000013098; -.
DR GeneID; 101338792; -.
DR CTD; 90196; -.
DR OMA; EYEMVGM; -.
DR OrthoDB; 542931at2759; -.
DR Proteomes; UP000245320; Chromosome 15.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005802; C:trans-Golgi network; IEA:TreeGrafter.
DR GO; GO:0006895; P:Golgi to endosome transport; IEA:TreeGrafter.
DR GO; GO:0043001; P:Golgi to plasma membrane protein transport; IEA:TreeGrafter.
DR GO; GO:0034067; P:protein localization to Golgi apparatus; IEA:TreeGrafter.
DR InterPro; IPR016973; Integral_membrane_SYS1.
DR InterPro; IPR019185; Integral_membrane_SYS1-rel.
DR PANTHER; PTHR12952:SF0; PROTEIN SYS1 HOMOLOG; 1.
DR PANTHER; PTHR12952; SYS1; 1.
DR Pfam; PF09801; SYS1; 1.
DR PIRSF; PIRSF031402; SYS1_homologue; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW ECO:0000256|PIRNR:PIRNR031402};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR031402};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR031402};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|PIRNR:PIRNR031402};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|PIRNR:PIRNR031402};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR031402}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR031402"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR031402"
FT TRANSMEM 92..110
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR031402"
FT TRANSMEM 116..138
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR031402"
SQ SEQUENCE 156 AA; 17530 MW; 45A9DC94B756A288 CRC64;
MAGQFRSYVW DPLLILSQIV LMQTVYYGSL GLWLALVDGL VRSSPSLDQM FDAEILGFST
PPGRLSTMSF VLNALTCALG LLYFIRRGKQ CLDFTVTVHF FHLLGCWFYS SRFPSALTWW
LVQAVCIALM AVIGEYLCMR SELKEIPLNS APKSSV
//
