ID A0A2V1C718_9HELO Unreviewed; 416 AA.
AC A0A2V1C718;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 02-APR-2025, entry version 22.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
DE Flags: Fragment;
GN ORFNames=DL98DRAFT_416483 {ECO:0000313|EMBL:PVH81474.1};
OS Cadophora sp. DSE1049.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Ploettnerulaceae; Cadophora.
OX NCBI_TaxID=1485229 {ECO:0000313|EMBL:PVH81474.1, ECO:0000313|Proteomes:UP000244409};
RN [1] {ECO:0000313|EMBL:PVH81474.1, ECO:0000313|Proteomes:UP000244409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSE1049 {ECO:0000313|EMBL:PVH81474.1,
RC ECO:0000313|Proteomes:UP000244409};
RX PubMed=29679020; DOI=10.1038/s41598-018-24686-4;
RA Knapp D.G., Nemeth J.B., Barry K., Hainaut M., Henrissat B., Johnson J.,
RA Kuo A., Lim J.H.P., Lipzen A., Nolan M., Ohm R.A., Tamas L.,
RA Grigoriev I.V., Spatafora J.W., Nagy L.G., Kovacs G.M.;
RT "Comparative genomics provides insights into the lifestyle and reveals
RT functional heterogeneity of dark septate endophytic fungi.";
RL Sci. Rep. 8:6321-6321(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
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DR EMBL; KZ804138; PVH81474.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V1C718; -.
DR STRING; 1485229.A0A2V1C718; -.
DR OrthoDB; 10009520at2759; -.
DR Proteomes; UP000244409; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20335; BRcat_RBR; 1.
DR CDD; cd22584; Rcat_RBR_unk; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51873; TRIAD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000244409};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 144..337
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PVH81474.1"
SQ SEQUENCE 416 AA; 46431 MW; 64E6A68F15943726 CRC64;
GSSKEPSEWE IVLKLHKDEL ERGLSTIRDR HISHSLARAV MIDANANNNA ISAAISQERL
AESDRAVALR LAGLPVPPPI QQALAGLGTP TPPQTPRSTD TGFEKIIDLI GEQSVYTTSV
KETKETDTPL KGSGTPKPLG SEGRLKGCVS CADEFEPAYI SQMPCKYDYC HFCVQRVVIN
SLVDEARYPP RCCKQPFDMD SMRQALTLEL ISGFYEKKAE FETVDRTYCS NPTCSAFLYP
VNIVGDKAAC PICFTKTCTI CKGPVHNGDC PQDTATQQVL ALANTEGWKR CENCKRMIEL
KHGCNHITCA CRAEWCYICG VAWKNCGCRM WEENRLLDRA NEIAARNPQP AGPARQDQVA
AIARAVTDNH ECDHDEWERV DGEWECDECG DELPYFIWRC TQCDIDACTR CRYNVL
//
