ID   A0A2Y9FVW1_TRIMA        Unreviewed;       725 AA.
AC   A0A2Y9FVW1;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   28-JAN-2026, entry version 29.
DE   RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN   Name=ZNF750 {ECO:0000313|RefSeq:XP_012410326.1};
OS   Trichechus manatus latirostris (Florida manatee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX   NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_012410326.1};
RN   [1] {ECO:0000313|RefSeq:XP_012410326.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (AUG-2025) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_012410326.1; XM_012554872.2.
DR   AlphaFoldDB; A0A2Y9FVW1; -.
DR   FunCoup; A0A2Y9FVW1; 612.
DR   STRING; 127582.A0A2Y9FVW1; -.
DR   GeneID; 105756174; -.
DR   KEGG; tmu:105756174; -.
DR   CTD; 79755; -.
DR   InParanoid; A0A2Y9FVW1; -.
DR   OrthoDB; 8933073at2759; -.
DR   Proteomes; UP000248480; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR   GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR   InterPro; IPR039363; ZNF750.
DR   InterPro; IPR039064; ZNF750_Znf.
DR   PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR   PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR   Pfam; PF15269; zf-C2H2_7; 1.
PE   4: Predicted;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          6..57
FT                   /note="Zinc finger protein 750-like zinc finger"
FT                   /evidence="ECO:0000259|Pfam:PF15269"
FT   REGION          65..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          116..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          363..425
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          466..631
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          645..725
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        67..95
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        387..398
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        487..498
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        617..630
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        715..725
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   725 AA;  77267 MW;  86A4216B24FDB966 CRC64;
     MSLLKERKPK KPHYIPRPPG KPFKYKCFQC PFTCNEKSHL FNHMKYGLCK NSITLVSEQD
     RVPKCAKSTS ADPKQTSPAD VTAKPASSRT ATNGLANFDP KLQPSFAKED VKENPGLHAH
     VSHKPPTQKP ALRKDAAPRS PAPDAGTQPV LEGMGRPSAF VPVGEHRLKG PEHPEVPEML
     ALPSPAAKAA SFHTKSAFHA PGYPWKAGSP FLPPEFPHKI PSTKAFGSIS PYAQPPLPEY
     SPHFYTEHGL ATIYSPYLLP GTPPEGDSPL LSSVYGAQDQ RHFLPLPGPV PKHLNTPPST
     YDHYRLFQQY HTSLPLPCGF YRPDSTFSSY GLKLPHVAGI ARDHGAHLLE ETTLVYPALS
     PSKLAPLSSH KKHTEFGKES PGPQAKDAPK DGQREAEGAK MSPRAGSAAT GSPGRPSPTN
     FTQTSHTCEG LYDLSSKPAP SPMGRLHLPE QTLTAFKPVK KCTDCPSPQT LAHRAGSPGS
     LEAANQEPPS QTGSTSDSAE AVPPGPQDGS SIAPLNLSKK PETKPAPAAH GHAYGDTPPA
     DMQDFPELQD MPLNLSVKDS CNALMPRPSF HSPPQDAGPA ATHKTATDSP QEGPPDSETS
     SDGPAGVPAT APPSGRASDE RAVDSSDEQK QTAAVALCQL AAYSPGKARV DSEKHSAQGP
     PAEQDAPTLG AKESRDVQSS ALRPKGQKRT GQKDSGKSQP GAKKAKPNDT ARVLTLRRRA
     RCLNA
//