ID A0A2Y9QZB6_TRIMA Unreviewed; 265 AA.
AC A0A2Y9QZB6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 10-JUN-2026, entry version 32.
DE SubName: Full=DNA dC->dU-editing enzyme APOBEC-3B-like {ECO:0000313|RefSeq:XP_023584683.1};
GN Name=LOC105756166 {ECO:0000313|RefSeq:XP_023584683.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023584683.1};
RN [1] {ECO:0000313|RefSeq:XP_023584683.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2026) to UniProtKB.
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DR RefSeq; XP_023584683.1; XM_023728915.1.
DR AlphaFoldDB; A0A2Y9QZB6; -.
DR STRING; 127582.A0A2Y9QZB6; -.
DR GeneID; 105756166; -.
DR KEGG; tmu:105756166; -.
DR InParanoid; A0A2Y9QZB6; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:TreeGrafter.
DR GO; GO:0000932; C:P-body; IEA:TreeGrafter.
DR GO; GO:0004126; F:cytidine deaminase activity; IEA:TreeGrafter.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:TreeGrafter.
DR GO; GO:0016554; P:cytidine to uridine editing; IEA:TreeGrafter.
DR GO; GO:0051607; P:defense response to virus; IEA:TreeGrafter.
DR GO; GO:0070383; P:DNA cytosine deamination; IEA:TreeGrafter.
DR GO; GO:0045869; P:negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; IEA:TreeGrafter.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 4.
DR InterPro; IPR059136; APOBEC3_CD_dom.
DR InterPro; IPR050610; APOBEC_Cyt_Deaminase.
DR InterPro; IPR002125; CMP_dCMP_dom.
DR PANTHER; PTHR13857:SF20; DNA DC-DU-EDITING ENZYME APOBEC-3G; 1.
DR PANTHER; PTHR13857; MRNA EDITING ENZYME; 1.
DR Pfam; PF18782; APOBEC3; 3.
DR PROSITE; PS51747; CYT_DCMP_DEAMINASES_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 1..103
FT /note="CMP/dCMP-type deaminase"
FT /evidence="ECO:0000259|PROSITE:PS51747"
SQ SEQUENCE 265 AA; 31194 MW; 1537A6635CEB28A0 CRC64;
MDTGIFLCYF SNDPRAREQY RTYLCYEVEL LDGNSWVLLY KSKGFLPKQL DPAQCHRVTW
FMSRSPCPDC AREVTAFLGK NSHVHLHIFA ASIYDYSGGY EEQLLSLWHA GAKIAIMTPT
DLMHQDIFQF NFNNNSLVCG QKQTYLCYEV ELLDDNSWVL LEGGRGFLNN QLDPAQCYRV
NCFMSRRPCF LCAWEVATFL GRNSHVSLHI FTSCTYEYFP SSECKHYWRT FVDNQGCPFE
PWNRLDKNSQ TIWKRLQRIL QNEYY
//
