ID A0A327KTJ2_9BRAD Unreviewed; 705 AA.
AC A0A327KTJ2;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 28-JAN-2026, entry version 32.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:RAI41274.1};
GN ORFNames=CH338_03700 {ECO:0000313|EMBL:RAI41274.1};
OS Rhodoplanes elegans.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Hyphomicrobiales; Nitrobacteraceae; Rhodoplanes.
OX NCBI_TaxID=29408 {ECO:0000313|EMBL:RAI41274.1, ECO:0000313|Proteomes:UP000248863};
RN [1] {ECO:0000313|EMBL:RAI41274.1, ECO:0000313|Proteomes:UP000248863}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11907 {ECO:0000313|EMBL:RAI41274.1,
RC ECO:0000313|Proteomes:UP000248863};
RA Lasarre B., Mckinlay J.B.;
RT "Draft Genome Sequences of Select Purple Nonsulfur Bacteria.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAI41274.1}.
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DR EMBL; NPEU01000021; RAI41274.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A327KTJ2; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000248863; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd15491; selB_III; 1.
DR FunFam; 3.40.50.300:FF:001064; Selenocysteine-specific translation elongation factor; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR048931; WHD_2nd_SelB_bact.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF21214; WHD_2nd_SelB_bact; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:RAI41274.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000248863}.
FT DOMAIN 1..168
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 646..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..663
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 677..686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 705 AA; 74946 MW; 4C5BA8F6B1A35A09 CRC64;
MIVGTAGHID HGKTSLVRAL TGVDTDRLKE EKARGISIDL GFAYVPTPDG GVLGFVDVPG
HERFVHTMVA GASGIDLVLL VVAGDDGVMP QTREHLAIVD LLGIRTGIVA LTKSDMVPPE
RRAEATAEIA AALAGTGLAD APIVPVSSVT GEGIEALRAQ LFDAARAFGR REAGDKKFRL
AVDRSFTLAG TGTVVTGTVL SGRVTVGDRV TVSPSGLSAR VRSIHAQNRP AGEGVAGDRC
ALNLAGDQIS KEAIRRGDMV LDPTLHAPAD RIDVTLRLLP GEAKPPTQWM PVRLHHASAE
VGARIVLLGD APPAPGREGR VQLVLETPIA AAAGDRFVLR DVSASRTIGG GRFLDLRGPA
RKRRTPERVA QLDALALDDP GAALAALLAR PPAHVELTGF ARDHALADDA LARLVETLGI
VRIADKDLLI GLAAPTWEAL TRDVVARLDA FHADNPDLPG VGLERLRLQI EPRLPAPAFR
SVLQGLARAG AAVLDGAWVR RPGHAVRLSE AEELIWQRIA PTLGGAERFK PPRVRDLAGL
FAIDEVLVRR VLRLTARTGR VDEVAHDHYF LRGTVAEMVT IARDLADQPS GVFTAAQFRD
RLDNGRKVAI QILEFFDRHG VTLRRGDLRR MNKHRLDLFG SLPAGDAQAG EAAGAEPDAT
AADADQHGRE SSPVGRPDFK SGRGREPVSG GFDSHSLPPS IRSAR
//
