ID A0A328BN56_9CAUL Unreviewed; 542 AA.
AC A0A328BN56;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 18-JUN-2025, entry version 25.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DJ019_05530 {ECO:0000313|EMBL:RAK67384.1};
OS Phenylobacterium kunshanense.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Caulobacterales; Caulobacteraceae; Phenylobacterium.
OX NCBI_TaxID=1445034 {ECO:0000313|EMBL:RAK67384.1, ECO:0000313|Proteomes:UP000249524};
RN [1] {ECO:0000313|EMBL:RAK67384.1, ECO:0000313|Proteomes:UP000249524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BUT-10 {ECO:0000313|EMBL:RAK67384.1,
RC ECO:0000313|Proteomes:UP000249524};
RA Lanie J.A., Ng W.-L., Kazmierczak K.M., Andrzejewski T.M., Davidsen T.M.,
RA Wayne K.J., Tettelin H., Glass J.I., Rusch D., Podicherti R., Tsui H.-C.T.,
RA Winkler M.E.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAK67384.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QFYS01000002; RAK67384.1; -; Genomic_DNA.
DR RefSeq; WP_111274995.1; NZ_QFYS01000002.1.
DR AlphaFoldDB; A0A328BN56; -.
DR OrthoDB; 9805942at2; -.
DR Proteomes; UP000249524; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P_dom.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR025908; Sensor_TM1.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR025919; Stimulus_sens_dom.
DR InterPro; IPR050428; TCS_sensor_his_kinase.
DR PANTHER; PTHR45436:SF5; SENSOR HISTIDINE KINASE TRCS; 1.
DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13755; Sensor_TM1; 1.
DR Pfam; PF13756; Stimulus_sens_1; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:RAK67384.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000249524};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 255..310
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 318..541
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..12
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 542 AA; 58113 MW; B252208AC75B04AB CRC64;
MASATDTGSP ETSAPDRAPP WERPRPARRF RGLPGSRLGR LILALNLLGL AILVSGALVL
NELRRGLVNA RIDSLTTQGE LIASILNQAA TVGEPEPQMD AALATELLQT LSNPKAQRAR
LFDSKGRLVA DSDWMADEVE RRDLPPARAR DDEEEGFRLM PRIAPPSRQE VERALQREVS
AALGGSHQAG MRAGDRGDRV VSVSIPIRHV RAVLGVVTLE ASDVDAIIAR ERAALIPFIL
IAVAVNVVSS LLLNSLVAQP VLRLARAADR VRAARARAIS LPDLARRDDE VGDLTRSLES
MTHALSERMD AIEAFAADVA HEIRNPLTSL RSAVETLDLV SDPAARDRLL GILKNDVQRL
DRLVTDISNA SRLDAELSRD QPRLLDLGRL IADIVATYEA TAKPGDVRVE FSPHLGMEAV
TVLGREGPLG QVLRNLVDNA RSFSPPGDVV TVGLASARGE ALVFVSDNGP GIPPENLETV
FERFYTSRPK GAAFGGNSGL GLSIARQIAQ AHGGALRAEN RTGEGGKVLG ALFTLTLPEA
RP
//
