ID A0A345PF80_9BACI Unreviewed; 395 AA.
AC A0A345PF80;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 02-APR-2025, entry version 23.
DE SubName: Full=NupC/NupG family nucleoside CNT transporter {ECO:0000313|EMBL:AXI08660.1};
GN ORFNames=CUC15_06930 {ECO:0000313|EMBL:AXI08660.1};
OS Oceanobacillus zhaokaii.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Oceanobacillus.
OX NCBI_TaxID=2052660 {ECO:0000313|EMBL:AXI08660.1, ECO:0000313|Proteomes:UP000253908};
RN [1] {ECO:0000313|Proteomes:UP000253908}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=160 {ECO:0000313|Proteomes:UP000253908};
RA Zhu W.;
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033}.
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DR EMBL; CP024848; AXI08660.1; -; Genomic_DNA.
DR RefSeq; WP_114915957.1; NZ_CP024848.1.
DR AlphaFoldDB; A0A345PF80; -.
DR KEGG; ocn:CUC15_06930; -.
DR OrthoDB; 9766455at2; -.
DR Proteomes; UP000253908; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:TreeGrafter.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR PANTHER; PTHR10590:SF23; NUPC_NUPG FAMILY NUCLEOSIDE CNT TRANSPORTER; 1.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000253908};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..80
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 90..188
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 192..392
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 395 AA; 42016 MW; 1174231FEB3478EA CRC64;
MGILLGALAI IVTLGISYLL SNDKKNVNFK SLGIMLVLQL LITWFMFSTT IGQAIINGIS
ALFNKLIEFG RAGINFILGG IEVGEGGVFF FNVLLLIIFF ATLLSVLTYL KILPFIIKYL
GGIVSKVTGL PKIESFNGVN SIFFGQSEAL IAIRSQFHHL TANRLFIVSA SAMNSVSASI
IGSYLQMLPA NYILVALPLN MFSALMVSSV IAPVKVPKEE DKVDISDVSD DKSLFEAMGN
GALEGGKIAL IVAAMIMAFI ASLELVNWLI QLVFAGVTLQ QILGYIFAPI GILMGIAPSE
VLQAGSIMGT KLVTNEFVAM LELQPLLGTL SEKTVGILTV FLTSFANFSS IGIMAGTVKG
IDNEKAAIVS GFGLKLLISG ILTSILSATV VGLFL
//
