ID A0A346PJ90_9EURY Unreviewed; 75 AA.
AC A0A346PJ90; A0A346PV13;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 18-JUN-2025, entry version 31.
DE RecName: Full=DNA-directed RNA polymerase subunit Rpo5 {ECO:0000256|HAMAP-Rule:MF_00025};
DE EC=2.7.7.6 {ECO:0000256|HAMAP-Rule:MF_00025};
DE AltName: Full=DNA-directed RNA polymerase subunit H {ECO:0000256|HAMAP-Rule:MF_00025};
GN Name=rpo5 {ECO:0000256|HAMAP-Rule:MF_00025};
GN Synonyms=rpoH {ECO:0000256|HAMAP-Rule:MF_00025};
GN ORFNames=AArc1_3284 {ECO:0000313|EMBL:AXR79585.1}, AArcMg_3378
GN {ECO:0000313|EMBL:AXR83358.1};
OS Natrarchaeobaculum sulfurireducens.
OC Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC Halobacteria; Halobacteriales; Natrialbaceae; Natrarchaeobaculum.
OX NCBI_TaxID=2044521 {ECO:0000313|EMBL:AXR79585.1, ECO:0000313|Proteomes:UP000258707};
RN [1] {ECO:0000313|Proteomes:UP000258707}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AArc1 {ECO:0000313|Proteomes:UP000258707};
RA Sorokin D.Y., Kublanov I.V., Roman P., Sinninghe Damste J.S.,
RA Golyshin P.N., Rojo D., Ciordia S., Mena Md.C., Ferrer M., Messina E.,
RA Smedile F., La Spada G., La Cono V., Yakimov M.M.;
RT "Phenotypic and genomic properties of facultatively anaerobic sulfur-
RT reducing natronoarchaea from hypersaline soda lakes.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000258613}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AArc-Mg {ECO:0000313|Proteomes:UP000258613};
RA Sorokin D.Y., Kublanov I.V., Roman P., Sinninghe Damste J.S.,
RA Golyshin P.N., Rojo D., Ciordia S., Mena M.D.C., Ferrer M., Messina E.,
RA Smedile F., La Spada G., La Cono V., Yakimov M.M.;
RT "Phenotypic and genomic properties of facultatively anaerobic sulfur-
RT reducing natronoarchaea from hypersaline soda lakes.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AXR79585.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=AArc-Mg {ECO:0000313|EMBL:AXR83358.1}, and AArc1
RC {ECO:0000313|EMBL:AXR79585.1};
RX PubMed=31166158;
RA Sorokin D.Y., Yakimov M., Messina E., Merkel A.Y., Bale N.J.,
RA Sinninghe Damste J.S.;
RT "Natronolimnobius sulfurireducens sp. nov. and Halalkaliarchaeum
RT desulfuricum gen. nov., sp. nov., the first sulfur-respiring alkaliphilic
RT haloarchaea from hypersaline alkaline lakes.";
RL Int. J. Syst. Evol. Microbiol. 69:2662-2673(2019).
CC -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the
CC transcription of DNA into RNA using the four ribonucleoside
CC triphosphates as substrates. {ECO:0000256|HAMAP-Rule:MF_00025}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) +
CC diphosphate; Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|HAMAP-Rule:MF_00025};
CC -!- SUBUNIT: Part of the RNA polymerase complex. {ECO:0000256|HAMAP-
CC Rule:MF_00025}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00025}.
CC -!- SIMILARITY: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase
CC subunit family. {ECO:0000256|HAMAP-Rule:MF_00025}.
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DR EMBL; CP024047; AXR79585.1; -; Genomic_DNA.
DR EMBL; CP027033; AXR83358.1; -; Genomic_DNA.
DR RefSeq; WP_117365512.1; NZ_CP024047.1.
DR AlphaFoldDB; A0A346PJ90; -.
DR GeneID; 37643868; -.
DR KEGG; nag:AArcMg_3378; -.
DR KEGG; nan:AArc1_3284; -.
DR OrthoDB; 30537at2157; -.
DR Proteomes; UP000258613; Chromosome.
DR Proteomes; UP000258707; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:TreeGrafter.
DR GO; GO:0006362; P:transcription elongation by RNA polymerase I; IEA:TreeGrafter.
DR GO; GO:0042797; P:tRNA transcription by RNA polymerase III; IEA:TreeGrafter.
DR Gene3D; 3.90.940.20; RPB5-like RNA polymerase subunit; 1.
DR HAMAP; MF_00025; RNApol_Rpo5_RPB5; 1.
DR InterPro; IPR014381; Arch_Rpo5/euc_Rpb5.
DR InterPro; IPR000783; RNA_pol_subH/Rpb5_C.
DR InterPro; IPR035913; RPB5-like_sf.
DR NCBIfam; NF007129; PRK09570.1; 1.
DR PANTHER; PTHR10535; DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1; 1.
DR PANTHER; PTHR10535:SF0; DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1; 1.
DR Pfam; PF01191; RNA_pol_Rpb5_C; 1.
DR SUPFAM; SSF55287; RPB5-like RNA polymerase subunit; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00025};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|HAMAP-Rule:MF_00025};
KW Nucleotidyltransferase {ECO:0000256|HAMAP-Rule:MF_00025,
KW ECO:0000313|EMBL:AXR83358.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000258613};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00025};
KW Transferase {ECO:0000256|HAMAP-Rule:MF_00025, ECO:0000313|EMBL:AXR83358.1}.
FT DOMAIN 2..73
FT /note="RNA polymerase subunit H/Rpb5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01191"
SQ SEQUENCE 75 AA; 8702 MW; 4A791905EBEE6BD5 CRC64;
MVDVSKHELV PEHTVLEEED LEEVLTEYDI DRTDLPKIKR NDPALPDDAE VNDVIEIVRD
SRTTDRAVVY RLVVE
//
