ID A0A346PQ81_9EURY Unreviewed; 161 AA.
AC A0A346PQ81; A0A346PFJ8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 02-APR-2025, entry version 23.
DE RecName: Full=Ribonuclease P protein component 2 {ECO:0000256|HAMAP-Rule:MF_00755};
DE Short=RNase P component 2 {ECO:0000256|HAMAP-Rule:MF_00755};
DE EC=3.1.26.5 {ECO:0000256|HAMAP-Rule:MF_00755};
DE AltName: Full=Pop5 {ECO:0000256|HAMAP-Rule:MF_00755};
GN Name=rnp2 {ECO:0000256|HAMAP-Rule:MF_00755};
GN ORFNames=AArc1_1973 {ECO:0000313|EMBL:AXR78293.1}, AArcMg_1666
GN {ECO:0000313|EMBL:AXR81676.1};
OS Natrarchaeobaculum sulfurireducens.
OC Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC Halobacteria; Halobacteriales; Natrialbaceae; Natrarchaeobaculum.
OX NCBI_TaxID=2044521 {ECO:0000313|EMBL:AXR81676.1, ECO:0000313|Proteomes:UP000258613};
RN [1] {ECO:0000313|Proteomes:UP000258707}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AArc1 {ECO:0000313|Proteomes:UP000258707};
RA Sorokin D.Y., Kublanov I.V., Roman P., Sinninghe Damste J.S.,
RA Golyshin P.N., Rojo D., Ciordia S., Mena Md.C., Ferrer M., Messina E.,
RA Smedile F., La Spada G., La Cono V., Yakimov M.M.;
RT "Phenotypic and genomic properties of facultatively anaerobic sulfur-
RT reducing natronoarchaea from hypersaline soda lakes.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000258613}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AArc-Mg {ECO:0000313|Proteomes:UP000258613};
RA Sorokin D.Y., Kublanov I.V., Roman P., Sinninghe Damste J.S.,
RA Golyshin P.N., Rojo D., Ciordia S., Mena M.D.C., Ferrer M., Messina E.,
RA Smedile F., La Spada G., La Cono V., Yakimov M.M.;
RT "Phenotypic and genomic properties of facultatively anaerobic sulfur-
RT reducing natronoarchaea from hypersaline soda lakes.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AXR81676.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=AArc-Mg {ECO:0000313|EMBL:AXR81676.1}, and AArc1
RC {ECO:0000313|EMBL:AXR78293.1};
RX PubMed=31166158;
RA Sorokin D.Y., Yakimov M., Messina E., Merkel A.Y., Bale N.J.,
RA Sinninghe Damste J.S.;
RT "Natronolimnobius sulfurireducens sp. nov. and Halalkaliarchaeum
RT desulfuricum gen. nov., sp. nov., the first sulfur-respiring alkaliphilic
RT haloarchaea from hypersaline alkaline lakes.";
RL Int. J. Syst. Evol. Microbiol. 69:2662-2673(2019).
CC -!- FUNCTION: Part of ribonuclease P, a protein complex that generates
CC mature tRNA molecules by cleaving their 5'-ends. {ECO:0000256|HAMAP-
CC Rule:MF_00755}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endonucleolytic cleavage of RNA, removing 5'-extranucleotides
CC from tRNA precursor.; EC=3.1.26.5; Evidence={ECO:0000256|HAMAP-
CC Rule:MF_00755};
CC -!- SUBUNIT: Consists of a catalytic RNA component and at least 4-5 protein
CC subunits. {ECO:0000256|HAMAP-Rule:MF_00755}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00755}.
CC -!- SIMILARITY: Belongs to the eukaryotic/archaeal RNase P protein
CC component 2 family. {ECO:0000256|HAMAP-Rule:MF_00755}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP024047; AXR78293.1; -; Genomic_DNA.
DR EMBL; CP027033; AXR81676.1; -; Genomic_DNA.
DR RefSeq; WP_117364381.1; NZ_CP024047.1.
DR AlphaFoldDB; A0A346PQ81; -.
DR GeneID; 37642148; -.
DR KEGG; nag:AArcMg_1666; -.
DR KEGG; nan:AArc1_1973; -.
DR OrthoDB; 19261at2157; -.
DR Proteomes; UP000258613; Chromosome.
DR Proteomes; UP000258707; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030677; C:ribonuclease P complex; IEA:UniProtKB-UniRule.
DR GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-UniRule.
DR GO; GO:0001682; P:tRNA 5'-leader removal; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.3250; Ribonuclease P, Pop5 subunit; 1.
DR HAMAP; MF_00755; RNase_P_2; 1.
DR InterPro; IPR002759; Pop5/Rpp14/Rnp2-like.
DR InterPro; IPR038085; Rnp2-like_sf.
DR Pfam; PF01900; RNase_P_Rpp14; 1.
DR SUPFAM; SSF160350; Rnp2-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00755};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000256|HAMAP-
KW Rule:MF_00755};
KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_00755, ECO:0000313|EMBL:AXR81676.1};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00755};
KW Reference proteome {ECO:0000313|Proteomes:UP000258613};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694, ECO:0000256|HAMAP-
KW Rule:MF_00755}.
SQ SEQUENCE 161 AA; 17699 MW; 98EBD6F027A5A97F CRC64;
MKHLPKHLQP RWRYLAIGLE AWPDAEIDRR AFQREVWYAG QNLLGDPGSA AADLSVIRFT
FANGEGEALV RVRRGETEPA RAAIACIDEI DGAAVGVRIR GISGTIRAAE ENYLGRRGQV
TEERNVVFGN EERVAVVCDG SADVRLDEAF TGATDLDYDL A
//
