ID A0A369RY48_9METZ Unreviewed; 226 AA.
AC A0A369RY48;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Spermine synthase {ECO:0000313|EMBL:RDD39192.1};
GN ORFNames=TrispH2_009004 {ECO:0000313|EMBL:RDD39192.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD39192.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD39192.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD39192.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD39192.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- SIMILARITY: Belongs to the spermidine/spermine synthase family.
CC {ECO:0000256|ARBA:ARBA00007867}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD39192.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NOWV01000144; RDD39192.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369RY48; -.
DR STRING; 287889.A0A369RY48; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0016768; F:spermine synthase activity; IEA:InterPro.
DR GO; GO:0006597; P:spermine biosynthetic process; IEA:InterPro.
DR Gene3D; 2.30.140.10; Spermidine synthase, tetramerisation domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR030374; PABS.
DR InterPro; IPR030373; PABS_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR035246; Spermidine_synt_N.
DR InterPro; IPR037163; Spermidine_synt_N_sf.
DR InterPro; IPR015576; Spermine_synthase_animal.
DR PANTHER; PTHR46315; SPERMINE SYNTHASE; 1.
DR PANTHER; PTHR46315:SF1; SPERMINE SYNTHASE; 1.
DR Pfam; PF17284; Spermine_synt_N; 1.
DR Pfam; PF01564; Spermine_synth; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01330; PABS_1; 1.
DR PROSITE; PS51006; PABS_2; 1.
PE 3: Inferred from homology;
KW Polyamine biosynthesis {ECO:0000256|PROSITE-ProRule:PRU00354};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00354}.
FT DOMAIN 118..226
FT /note="PABS"
FT /evidence="ECO:0000259|PROSITE:PS51006"
SQ SEQUENCE 226 AA; 25741 MW; 330371AB6F97DCCD CRC64;
MADDKVLHYM FDFRSIQTSL TPEAFIADAS QFMKQKDFNL VCSSPLPHGQ LLVWTGPDRS
HAVIRLYQDI NRITVDITKP LPDGKTIIFS EDDEREIKSL FQGNSKSYPA IQRCRDLDIY
VPTCDNRLVE YDFDKVVVNV DTQFQNVKIC HSPQYGNMLL LDDDPNLAES DIAYTKAITG
NDTQDYTDKT VLILGGGDGG ILNELLKQSP KYVTMVEISF IIFFYF
//
