ID A0A370TBS9_9HELO Unreviewed; 701 AA.
AC A0A370TBS9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 02-APR-2025, entry version 25.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=BP5553_09704 {ECO:0000313|EMBL:RDL31495.1};
OS Venustampulla echinocandica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Pleuroascaceae; Venustampulla.
OX NCBI_TaxID=2656787 {ECO:0000313|EMBL:RDL31495.1, ECO:0000313|Proteomes:UP000254866};
RN [1] {ECO:0000313|EMBL:RDL31495.1, ECO:0000313|Proteomes:UP000254866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BP 5553 {ECO:0000313|EMBL:RDL31495.1,
RC ECO:0000313|Proteomes:UP000254866};
RX PubMed=30018880; DOI=10.5598/imafungus.2018.09.01.13;
RA Wingfield B.D., Bills G.F., Dong Y., Huang W., Nel W.J.,
RA Swalarsk-Parry B.S., Vaghefi N., Wilken P.M., An Z., de Beer Z.W.,
RA De Vos L., Chen L., Duong T.A., Gao Y., Hammerbacher A., Kikkert J.R.,
RA Li Y., Li H., Li K., Li Q., Liu X., Ma X., Naidoo K., Pethybridge S.J.,
RA Sun J., Steenkamp E.T., van der Nest M.A., van Wyk S., Wingfield M.J.,
RA Xiong C., Yue Q., Zhang X.;
RT "IMA Genome-F 9: Draft genome sequence of Annulohypoxylon stygium,
RT Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis
RT basicola), Ceratocystis smalleyi, two Cercospora beticola strains,
RT Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina,
RT and Morchella septimelata.";
RL IMA Fungus 9:199-223(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDL31495.1}.
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DR EMBL; NPIC01000012; RDL31495.1; -; Genomic_DNA.
DR RefSeq; XP_031865626.1; XM_032018327.1.
DR AlphaFoldDB; A0A370TBS9; -.
DR STRING; 2656787.A0A370TBS9; -.
DR GeneID; 43602553; -.
DR OrthoDB; 9977870at2759; -.
DR Proteomes; UP000254866; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd22584; Rcat_RBR_unk; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000254866};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 213..412
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 217..263
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 72..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 413..450
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 604..649
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 81..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 701 AA; 79957 MW; C99C10A603F493B0 CRC64;
MAPVPVSVLR KCSLSDVQRA DGHGPAPAEY SNRDYVREVL QLQRQLGNDQ AEALVDETLV
QEAETWGIAI TTTVPGPATS KGGQDQNAAD NSNPPSKSTV ALHHTRCPSS GSHETNSTVG
TSRSSREQAD NPARPQFRRR SSSKKTLSFS DYEKYLAEVR AQDNTQVEYV APPAPKDPAP
TLFSLSTRKS HAGIKKRLKR SFSVRRRSST QDDINFCICC RDEFGKNSKE LHTLPCGHSY
CDTCLRVITT QAVTDESKMP PRCCSQPVPS TIIKTVLTKG EQYSFMKSVL QFSTPWEARI
FCPNTACGEF VPGRSRVDPK HPFEVMCRKC RTKACSTCKR AAHAFGQDCP ADWELDAVLQ
MGEKSGWRRC YKCRTLVELT QGCSHITCRC KAQFCYICGA VWNPVVGCPN YCSGEEELER
RRLEEEARMA ELAKEKAEME EAERIEAAEK VAAEERTRRS SELNALRAQQ INEHDRFIAF
ERKMKWMMWT RHGQLKLDIL DRYGEMLSKM KERHIRTATH LEDRQVGAEL ELRASHKQAE
RSVQIRLRHM EAYCDGLGRN ASGSNPARVV TERDLRELGQ QYSVRDDLER LHQSKINVMR
DKQSKQMEEL LARQEDELDK LATKQAEELE GLEERFVNEE DGLADLFQQR RARLRWRWGI
TEEILRKQLE AREKVKFAMM KPVEWPELES NQDDGLEAVS E
//
