ID A0A371ILZ5_9FIRM Unreviewed; 446 AA.
AC A0A371ILZ5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 28-JAN-2026, entry version 25.
DE SubName: Full=Thioether cross-link-forming SCIFF peptide maturase {ECO:0000313|EMBL:RDY21498.1};
GN Name=scfB {ECO:0000313|EMBL:RDY21498.1};
GN ORFNames=BBG48_004955 {ECO:0000313|EMBL:RDY21498.1};
OS Criibacterium bergeronii.
OC Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
OC Filifactoraceae; Criibacterium.
OX NCBI_TaxID=1871336 {ECO:0000313|EMBL:RDY21498.1, ECO:0000313|Proteomes:UP000093352};
RN [1] {ECO:0000313|EMBL:RDY21498.1, ECO:0000313|Proteomes:UP000093352}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCRI-22567 {ECO:0000313|EMBL:RDY21498.1,
RC ECO:0000313|Proteomes:UP000093352};
RX PubMed=27587833;
RA Maheux A.F., Berube E., Boudreau D.K., Raymond F., Corbeil J., Roy P.H.,
RA Boissinot M., Omar R.F.;
RT "Draft Genome Sequence of Criibacterium bergeronii gen. nov., sp. nov.,
RT Strain CCRI-22567T, Isolated from a Vaginal Sample from a Woman with
RT Bacterial Vaginosis.";
RL Genome Announc. 4:e00959-e00916(2016).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDY21498.1}.
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DR EMBL; MBEW02000007; RDY21498.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A371ILZ5; -.
DR STRING; 1871336.BBG48_06315; -.
DR Proteomes; UP000093352; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21124; SPASM_CteB-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR000385; MoaA_NifB_PqqE_Fe-S-bd_CS.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR058240; rSAM_sf.
DR InterPro; IPR024025; SCIFF_rSAM_maturase.
DR InterPro; IPR047602; SPASM_CteB-like.
DR InterPro; IPR023867; Sulphatase_maturase_rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR NCBIfam; TIGR03974; rSAM_six_Cys; 1.
DR PANTHER; PTHR43273; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR PANTHER; PTHR43273:SF8; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SFLD; SFLDG01384; thioether_bond_formation_requi; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS01305; MOAA_NIFB_PQQE; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000093352};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 80..305
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 446 AA; 51116 MW; 180B9FD178E87701 CRC64;
MNGLNIVLDI NSGAVHVFDD ISYDIVEDAY DKEFSYITKK YKQYSKQDLK ESYDELMDLK
NNSQLFVEGD YIDDLSILAE DVIKAMCLHV SHDCNLRCTY CFASQGDFGG DRELMSEEVG
KKALDFLLEK SGKRKNLEVD FFGGEPLMNF EVVKKLVEYG NAQAEKKGKY FRFTITTNGL
ALNDDIINYI NENMHNVVLS LDGRREINDK NRPLINGKGS YEYIVPKFQK LIEQRPKDKY
YYVRGTFTRD NLDFSKDVKH YKDLGFELTS IEPVVGEDEF AIREEDLPAI LAEYESLAKD
YADMQAKDEP FKLFHFMVDL SQGPCVIKRV RGCGAGGEYL AITPTGDIYP CHQFVGEEEF
KMGNILDENL QLPEKMRGTF KSANVFTKDE CKNCWARYYC SGGCHANALH FNKDIQKPYE
TGCIMQRKRL ECAIMVEAYK AINGAN
//
