ID A0A371S4W1_9BACI Unreviewed; 382 AA.
AC A0A371S4W1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 18-JUN-2025, entry version 26.
DE SubName: Full=Galactonate dehydratase {ECO:0000313|EMBL:RFB12744.1};
DE EC=4.2.1.6 {ECO:0000313|EMBL:RFB12744.1};
GN ORFNames=DZB84_17925 {ECO:0000313|EMBL:RFB12744.1};
OS Bacillus sp. HNG.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=2293325 {ECO:0000313|EMBL:RFB12744.1, ECO:0000313|Proteomes:UP000263943};
RN [1] {ECO:0000313|EMBL:RFB12744.1, ECO:0000313|Proteomes:UP000263943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HNG {ECO:0000313|EMBL:RFB12744.1,
RC ECO:0000313|Proteomes:UP000263943};
RA Gagnon H.N., Maines B.A., Sevigny J.L.;
RT "Genome Assembly of Bacillus sp. HNG.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFB12744.1}.
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DR EMBL; QUQV01000011; RFB12744.1; -; Genomic_DNA.
DR RefSeq; WP_116353808.1; NZ_QUQV01000011.1.
DR AlphaFoldDB; A0A371S4W1; -.
DR OrthoDB; 9775391at2; -.
DR Proteomes; UP000263943; Unassembled WGS sequence.
DR GO; GO:0008869; F:galactonate dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR GO; GO:0034194; P:D-galactonate catabolic process; IEA:InterPro.
DR CDD; cd03325; D-galactonate_dehydratase; 1.
DR FunFam; 3.30.390.10:FF:000003; D-galactonate dehydratase; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR034593; DgoD-like.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR023592; Galactonate_deHydtase.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR NCBIfam; NF010624; PRK14017.1; 1.
DR PANTHER; PTHR48080:SF2; D-GALACTONATE DEHYDRATASE; 1.
DR PANTHER; PTHR48080; D-GALACTONATE DEHYDRATASE-RELATED; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDF00003; D-galactonate_dehydratase; 1.
DR SFLD; SFLDG00179; mandelate_racemase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00909; MR_MLE_2; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:RFB12744.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000263943}.
FT DOMAIN 125..230
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 382 AA; 42526 MW; 993E021002EE1E1C CRC64;
MKITSLTLYK VPPRWLFLKI ETDEGISGWG EPIVEGRADT VRACVQEVSD YLVGKDPLRI
EDHWQVLYRG GFYRGGPILM SAISGIEQAL WDIKGKYYHI PVYEMLGGKA REKIRVYSWI
GGDRPTDVAH AAKEKADAGF TAVKMNATEE MDYIDTHSKV EAAVQRIAAV REAVGKEFGI
ALDFHGRVHK SMAKILVKEL EPFRPMFIEE PVLPENNEAL REIARHTVCP IATGERQYSR
WGFKQLLMDG YVDIIQPDLS HAGGILECKK IAAMAEAFDV SVAPHCPLGP IALASSFQLD
ACTPNVVIQE QSLGIHYNQG SDLLDYLTDP SVFKYTNGFV EIPEGPGLGI DVNEEAVLAA
AEKGHDWKNP IWRNEDGSVA EW
//
